3-Bromo-4-fluorotoluene
- Product Name
- 3-Bromo-4-fluorotoluene
- CAS No.
- 452-62-0
- Chemical Name
- 3-Bromo-4-fluorotoluene
- Synonyms
- 3-Bromo-4-fluorotolu;3-Bromo-4-fluotoluene;3-Bromo-4-flurotoluene;3-BROMO-4-FLUOROTOLUENE;3-broMo -4-fluorine toluene;3-Bromo-4-fluorotoluene,99%;3-Bromo-4-fluorotoluene >3-Bromo-4-fluorotoluene 99%;2-BROMO-1-FLUORO-4-METHYLBENZENE;Benzene, 2-bromo-1-fluoro-4-methyl-
- CBNumber
- CB4171267
- Molecular Formula
- C7H6BrF
- Formula Weight
- 189.02
- MOL File
- 452-62-0.mol
3-Bromo-4-fluorotoluene Property
- Boiling point:
- 169 °C/756 mmHg (lit.)
- Density
- 1.507 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.531(lit.)
- Flash point:
- 164 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid
- Specific Gravity
- 1.52
- color
- Clear colorless to light yellow
- BRN
- 1680604
- InChI
- InChI=1S/C7H6BrF/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3
- InChIKey
- QLRKALMVPCQTMU-UHFFFAOYSA-N
- SMILES
- C1(F)=CC=C(C)C=C1Br
- CAS DataBase Reference
- 452-62-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29039990
- Storage Class
- 10 - Combustible liquids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 337013
- Product name
- 3-Bromo-4-fluorotoluene
- Purity
- 99%
- Packaging
- 5g
- Price
- $31.2
- Updated
- 2023/06/20
- Product number
- B1945
- Product name
- 3-Bromo-4-fluorotoluene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $64
- Updated
- 2025/07/31
- Product number
- B693478
- Product name
- 3-Bromo-4-fluorotoluene
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B693478
- Product name
- 3-Bromo-4-fluorotoluene
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B693478
- Product name
- 3-Bromo-4-fluorotoluene
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
3-Bromo-4-fluorotoluene Chemical Properties,Usage,Production
Chemical Properties
colorless to light yellow liqui
Uses
3-Bromo-4-fluorotoluene was employed as starting reagent in the synthesis of [4-fluoro-3-(trimethylsilyl)benzyl]guanidine. It was also employed as benzyne precursor in the synthesis of 6-methyl-1,2,3,4-tetrahydro-2,3-(benzylidenedioxy)-1,4-ethenonapthalene.
Synthesis
542-56-3
583-68-6
452-62-0
Example 4: 84 g of 2-bromo-4-methylaniline and 54.5 g of isobutyl nitrite were slowly added dropwise through two dropping funnels, respectively, to a solution of 160 g of dimethoxyethane containing 37 g of boron trifluoride and 10.3 g of hydrogen fluoride at a temperature of -5°C to 0°C (the dropping process lasted for 1 hour). After the dropwise addition, the reaction mixture was continued to be stirred at 0°C for 15 min, followed by diafiltration. The resulting crystalline diazonium salt was washed with 50 mL of pre-cooled dimethoxyethane and then dried under vacuum at room temperature. A diazonium salt product of 122.5 g was obtained in a yield of 86% of the theoretical value. The decomposition reaction was carried out according to the method of Example 6, resulting in 3-bromo-4-fluorotoluene in 92.4% yield of the theoretical value.
References
[1] Patent: US4476320, 1984, A
3-Bromo-4-fluorotoluene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-4-fluorotoluene manufacturers
- Product
- 3-Bromo-4-fluorotoluene 452-62-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-04
- Product
- 3-Bromo-4-fluorotoluene 452-62-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-07
- Product
- 3-Bromo-4-fluorotoluene 452-62-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 50mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-08