Dorzolamide

Product Name: Dorzolamide
CAS No.: 120279-96-1
Chemical Name: Dorzolamide
Synonyms: C06969;DORZOLAMIDE;4S,6S-Dorzolamide;Dorzolamide-d5 Maleate;Dorzolamide >=98% (HPLC);Dorzalamide hydrochloride;DORZOLAMIDE(SUBJECTTOPATENTFREE);Dorzolamide Impurity A Hydrochloride;(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-7,;7-dioxide-4H-Thieno[2,3-b]thiopyran-2-sulfonamide/ Dorzolamide
CBNumber: CB4174657
Molecular Formula: C10H16N2O4S3
Formula Weight: 324.44
MOL File: 120279-96-1.mol

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Dorzolamide Property

Boiling point:: 575.8±60.0 °C(Predicted)
Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: room temp
solubility: DMSO: soluble5mg/mL (clear solution, warmed)
pka: pKa 6.35 (Uncertain);8.50 (Uncertain)
form: powder
color: white to beige
optical activity: [α]/D -25 to -35°, c = 1 in methanol
CAS DataBase Reference: 120279-96-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
RTECS: XJ9095169

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0468
Product name: Dorzolamide
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $96.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0468
Product name: Dorzolamide
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $393
Updated: 2024/03/01

TRC

Product number: D535103
Product name: Dorzolamide
Packaging: 25mg
Price: $530
Updated: 2021/12/16

TRC

Product number: D535103
Product name: Dorzolamide
Packaging: 50mg
Price: $1035
Updated: 2021/12/16

TRC

Product number: D535103
Product name: Dorzolamide
Packaging: 100mg
Price: $1705
Updated: 2021/12/16

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Dorzolamide Chemical Properties,Usage,Production

Uses

Carbonic anhydrase inhibitor.

Uses

Dorzolamide is an intermediate in synthesizing N-Acetyl Dorzolamide (A173640), a useful synthetic compound.

Definition

ChEBI: 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration . A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension.

brand name

Trusopt (Merck).

Biological Activity

Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.

Dorzolamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Dorzolamide Suppliers

China 80 Europe 2 Germany 1 India 10 South Korea 1 United Kingdom 5 United States 20 Global 119

Leancare Ltd.

Tel: --
Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

CARBONE SCIENTIFIC CO.,LTD

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Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

ETA SCIENTIFIC Co.,Ltd

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Fax: --
Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
Advantage: 34

UK GREEN SCIENTIFIC CO.,LIMITED

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Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Eurolabs Limited

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Fax: --
Country: United Kingdom
ProdList: 6309
Advantage: 46

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View Lastest Price from Dorzolamide manufacturers

Career Henan Chemical Co

Product: Dorzolamide 120279-96-1
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 100kg
Release date: 2020-01-07

120279-96-1, DorzolamideRelated Search:

Dorzolamide Hydrochloride METSULFURON METHYL Methyl acetate Acrylamide Erucamide Boc-D-Glutamine Nicotinamide 1,4-Dioxane Thiophanate-methyl Tribenuron methyl Ceramide N,N-Dimethylformamide Polyamide Methyl salicylate Selenium dioxide Kresoxim-methyl Polyacrylamide (4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3-B]Thiopyran7,7Dioxide

DORZOLAMIDE

DORZOLAMIDE(SUBJECTTOPATENTFREE)

4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-

4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S-trans)-

4S,6S-Dorzolamide

(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide

(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-7,

Dorzalamide hydrochloride

7-dioxide-4H-Thieno[2,3-b]thiopyran-2-sulfonamide/ Dorzolamide

(2r,4r)-2-ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide

C06969

(2S,4S)-4-(ethylaMino)-2-Methyl-1,1-dioxo-2H,3H,4H-1$l^{6},7-thieno[2,3-b][1$l^{6}]thiopyran-6-sulfonaMide

(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide

Dorzolamide >=98% (HPLC)

Dorzolamide-d5 Maleate

Dorzolamide Impurity A Hydrochloride

DorzolamideQ: What is Dorzolamide Q: What is the CAS Number of Dorzolamide Q: What is the storage condition of Dorzolamide Q: What are the applications of Dorzolamide

120279-96-1

12079-96-1

C10H16N2O4S3