N-TERT-BUTYLTRIMETHYLSILYLAMINE Property

Boiling point:

118-119 °C(lit.)

Density 

0.762 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.406(lit.)

Flash point:

80 °F

form 

liquid

pka

13.25±0.70(Predicted)

color 

Clear, colourless

BRN 

1734528

Safety

Hazard Codes 

C

Risk Statements 

10-34

Safety Statements 

16-26-36/37/39-45

RIDADR 

UN 2733 3/PG 3

WGK Germany 

3

F 

10-21

HazardClass 

3.2

PackingGroup 

III

HS Code 

2931900090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

N-TERT-BUTYLTRIMETHYLSILYLAMINE Chemical Properties,Usage,Production

Uses

N-tert-Butyltrimethylsilylamine may be used in the preparation of selenium and tellurium chalcogenides and the facile synthesis of N-alkylaminomethylphosphonates.

Preparation

N-tert-Butyltrimethylsilylamine is prepared by the reaction of the parent amines with n-Butyllithium in THF/hexane. The parent amines are prepared by the reaction of lithium t-butylamide and the corresponding chlorosilanes (eq 1).

General Description

N-tert-Butyltrimethylsilylamine (Me₃SiNH-t-Bu) reacts with [Cp*Rh(H₂O)₃](OTf)₂ in acetone to yield a hydroxyl-capped half-cubane [Cp*3Rh₃(μ-OH)3(μ₃-OH)](OTf)₃(t-BuNH₃).

storage

N-tert-Butyltrimethylsilylamine reacts readily with protic solvents, especially water, and must be maintained in a dry environment. It is thermally stable. Use in a fume hood.

Purification Methods

Best purified by distillation.