ChemicalBook > CAS DataBase List > M40
M40
- Product Name
- M40
- CAS No.
- 143896-17-7
- Chemical Name
- M40
- Synonyms
- M40;CDCBM6;CSCSC1;MGC16435;M40（TFA）;MGC117247;M40?, >98%;OK/SW-cl.56;GWTLNSAGYLLGPPPALALA-NH2;Tubulin, GST tagged human
- CBNumber
- CB4190842
- Molecular Formula
- C94H145N23O24
- Formula Weight
- 1981.3
- MOL File
- 143896-17-7.mol
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M40 Property
- storage temp.
- −20°C
- form
- Powder
- color
- White to off-white
- biological source
- human
- Water Solubility
- Soluble to 1 mg/ml in water
- Sequence
- Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SRP5148
- Product name
- Tubulin, GST tagged human
- Purity
- recombinant, expressed in <I>E. coli</I>, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 20 μg
- Price
- $354
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SRP5148
- Product name
- Tubulin, GST tagged human
- Purity
- recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 20μG
- Price
- $345
- Updated
- 2024/03/01
Tocris
- Product number
- 3425
- Product name
- M40
- Packaging
- 1
- Price
- $227
- Updated
- 2021/12/16
Usbiological
- Product number
- 255744
- Product name
- M40
- Packaging
- 1mg
- Price
- $480
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0001397
- Product name
- GALANIN RECEPTOR LIGAND M40
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $721.59
- Updated
- 2021/12/16
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M40 Chemical Properties,Usage,Production
Uses
GST tagged tubulin has been used in Western blotting and in mass spec as a control.
Biological Activity
Tubulin-β 1 (TUBB1) interaction with microtubule-associated proteins (MAPs) such as tau is fundamental for microtubule structure and function. It has a role in the formation of the cytoskeleton. Studies revealed th at TUBB1 is the target of various antitubulin agents used in the treatment of cancer. Subsequent studies have also concluded th at TUBB1 mutations in clinical samples are rare, and unlikely to contribute to drug resistance.
in vivo
M40 (0.1-1 nmol, intracisternal injection, single dose) blocks selectively the central cardiovascular responses induced by galanin-(1–15) in Sprague-Dawley rats models, according to the recognization of galanin receptor in N-terminus[1].
M40 (2-8 nmol, intraventricular or intrahippocampal, single dose) exhibits antagonist efficacy against galanin on memory tasks in sprague-dawley rats models, exhibits potency in alleviating the cognitive deficits associated with Alzheimer's disease[2].
| Animal Model: | Vasopressor and tachycardia induced by galanin in Sprague-Dawley rats[1] |
| Dosage: | 0.1-1 nmol |
| Administration: | Intracisternal injection, single dose |
| Result: | Blocked the feeding effects of galanin in the hypothalamus and amygdala. Reduced vasopressor response and heart rate induced by galanin-(1-15), but not those effects induced by galanin-(1-29). |
| Animal Model: | Memory impairment induced by galanin in rats model[2] |
| Dosage: | 2-8 nmol |
| Administration: | intraventricular or intrahippocampal, single dose |
| Result: | Blocked the impairment in choice accuracy. |
storage
Store at -20°C
M40 Preparation Products And Raw materials
Raw materials
Preparation Products
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M40 Suppliers
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 21-61263452 13641803416
- Fax
- 86-21-61263399
- ymbetter@glbiochem.com
- Country
- China
- ProdList
- 9981
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15402
- Advantage
- 60
- Tel
- 0551-65326643 18156095617
- Fax
- 0551-65326641
- info@cellmano.com
- Country
- China
- ProdList
- 1010
- Advantage
- 55
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4861
- Advantage
- 58
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 17705183659
- Fax
- 84523390
- sales@njleonbiotech.com
- Country
- China
- ProdList
- 5501
- Advantage
- 55
- Tel
- 025-58361106-805 15951641583
- Fax
- 025-58361106-806
- zhao.xu@njpeptide.com
- Country
- China
- ProdList
- 9979
- Advantage
- 55
- Tel
- +86-17380623303
- Fax
- 028-62328193
- Caroline@youngshechem.com
- Country
- China
- ProdList
- 4802
- Advantage
- 58
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View Lastest Price from M40 manufacturers
Career Henan Chemical Co
- Product
- M40 143896-17-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-13
143896-17-7, M40Related Search:
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ANTI-DFF40/CAD (AA 147-164),ANTI-DFF40/CAD (I18) HUMAN, AA 147-164
ANTI-DFF40 (AB-1) (331-344) RABBIT PAB,ANTI-DFF40
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ANTI-DFF40
ANTI-HUMAN CD40, BIOTIN CONJUGATE