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(R)-1-Boc-3-methylpiperazine

Product Name
(R)-1-Boc-3-methylpiperazine
CAS No.
163765-44-4
Chemical Name
(R)-1-Boc-3-methylpiperazine
Synonyms
tert-butyl (R)-3-methylpiperazine-1-carboxylate;(R)-4-N-BOC-2-METHYLPIPERAZINE;(R)-tert-butyl 3-Methylpiperazine-1-carboxylate;(R)-4-Boc-2-Methylpi;(R)-N-BOC-2-METHYLPIPERAZINE;(R)-1-BOC-3-METHYLPIPERAZINE;(R)-4-BOC-2-METHYLPIPERAZINE;(R)-N4-BOC-2-METHYLPIPERAZINE;(R)-3-Methyl-1-Boc-piperazine;(3R)-1-BOC-3-METHYLPIPERAZINE
CBNumber
CB4192376
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
163765-44-4.mol
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(R)-1-Boc-3-methylpiperazine Property

Melting point:
40-45 °C
Boiling point:
268.7±15.0 °C(Predicted)
Density 
0.997±0.06 g/cm3(Predicted)
Flash point:
223 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
8.52±0.40(Predicted)
form 
Crystalline Powder
color 
White
optical activity
[α]/D +16±2°, c = 1 in dioxane
InChIKey
FMLPQHJYUZTHQS-MRVPVSSYSA-N
CAS DataBase Reference
163765-44-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-36/37/38
Safety Statements 
26-39-37/39
WGK Germany 
3
F 
10-34
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H27350
Product name
(R)-(+)-1-Boc-3-methylpiperazine, 97%
Packaging
1g
Price
$69.65
Updated
2024/03/01
Alfa Aesar
Product number
H27350
Product name
(R)-(+)-1-Boc-3-methylpiperazine, 97%
Packaging
5g
Price
$212.65
Updated
2024/03/01
Sigma-Aldrich
Product number
674761
Product name
(R)-1-Boc-3-methylpiperazine
Purity
97%
Packaging
1g
Price
$90.7
Updated
2024/03/01
TRC
Product number
B656835
Product name
(R)-4-Boc-2-methylpiperazine
Packaging
10g
Price
$160
Updated
2021/12/16
TRC
Product number
B656835
Product name
(R)-4-Boc-2-methylpiperazine
Packaging
250g
Price
$1375
Updated
2021/12/16
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(R)-1-Boc-3-methylpiperazine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

(R)-4-Boc-2-methylpiperazine is a reagent used in organic synthesis. Used in the synthesis of orally bioavailable inhibitors of 11-β-hydroxysteroid. (R)-4-Boc-2-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

To a solution of (R)-methylpiperazine (400 mg) in dichloromethane (20 mL) at 0 ℃ was added di-tert-butyl dicarbonate (871 mg). The reaction was stirred at room temperature for 4 h and then quenched with water (20 mL), followed by extraction into dichloromethane (2 x 40 mL). The combined organics were washed with saturated aqueous brine solution (40 mL), dried (MgSO4), and concentrated to give (R)-1-Boc-3-methylpiperazine as a white solid (669 mg, 84%).

(R)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-Boc-3-methylpiperazine Suppliers

China 219 Europe 2 France 1 Germany 4 India 2 Japan 1 Switzerland 1 United Kingdom 11 United States 44 Global 285
SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from (R)-1-Boc-3-methylpiperazine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
(R)-4-Boc-2-methylpiperazine 163765-44-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-17
Shanghai UCHEM Inc.
Product
(R)-4-Boc-2-methylpiperazine 163765-44-4
Price
US $37.00-788.00/g
Min. Order
10g
Purity
0.99
Supply Ability
25kg
Release date
2023-12-18
Honest Joy Holdings Limited
Product
(R)-4-N-Boc-2-methylpiperazine 163765-44-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99.3%
Supply Ability
100 tons
Release date
2022-02-08

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  • (R)-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (R)-N-BOC-2-METHYLPIPERAZINE
  • (R)-N4-BOC-2-METHYLPIPERAZINE
  • TERT-BUTYL (R)-3-METHYL-1-PIPERAZINECARBOXYLATE
  • (R)-4-N-BOC-2-METHYLPIPERAZINE
  • (R)-4-BOC-2-METHYLPIPERAZINE
  • (R)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (R)-1-BOC-3-METHYLPIPERAZINE
  • (R)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE
  • (R)-1-N-BOC-3-METHYLPIPERAZINE
  • (R)-3-Methyl-1-Boc-piperazine
  • (3R)-1-BOC-3-METHYLPIPERAZINE
  • 4-BOC-2-(R)-METHYL-PIPERAZINE
  • 1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3R)-
  • (S)-1-BOC-3-METHYL-PIPERAZINE,(R)-1-Boc-3-methylpiperazine
  • (R)-4-N-Boc-2-methylpiperazine (R )-4-N-Boc-2-methyl piperazine
  • (R)-2-Methylpiperazine, N4-BOC protected
  • (R)-1-Boc-3-methylpiperazine, tert-Butyl (R)-3-methyl-1-piperazinecarboxylate
  • (R)-4-Boc-2-piperazinecarboxylic acid
  • (R)-3-Methyl-Piperazine-1-Carbo
  • (3R)-3-Methylpiperazine, N1-BOC protected
  • tert-Butyl (R)-3-methyl-1-piperazinecarboxylate acid
  • tert-Butyl (3R)-3-methylpiperazine-1-carboxylate
  • (R)-tert-butyl 3-Methylpiperazine-1-carboxylate
  • (R)-4-N-BOC-2-METHYL-PIPERAZINE-HCl
  • (R)-4-Boc-2-Methylpi
  • (<i>R</i>)-(+)-1-Boc-3-Methylpiperazine
  • (R)-4-N-Boc-2-Methyl-piperazine/(R)-1-Boc-3-Methylpiperazine
  • (R)-butyl 3-Methylpiperazine-1-carboxylate
  • (R)-(+)-1-Boc-3-methylpiperazine,97%
  • tert-butyl (R)-3-methylpiperazine-1-carboxylate
  • tert-Butyl (3R)-3-methylpiperazine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-methylpiperazine
  • 1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3R)- (9CI, ACI)
  • 3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3R)- (9CI ACI)
  • (R)-tert-butyl-2- methylpiperazine-4-carboxylate
  • 163765-44-4
  • 345-75-7
  • C10H20N2O2
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Heterocyclic Building Blocks
  • Piperazines
  • Piperazines
  • Piperaizine
  • Piperazine series
  • pharmacetical