ChemicalBook > CAS DataBase List > 1,3-Dimethyl-1H-pyrazol-5-amine

1,3-Dimethyl-1H-pyrazol-5-amine

Product Name
1,3-Dimethyl-1H-pyrazol-5-amine
CAS No.
3524-32-1
Chemical Name
1,3-Dimethyl-1H-pyrazol-5-amine
Synonyms
AKOS B024294;AKOS PAO-1219;AKOS BBS-00004675;BUTTPARK 29\04-74;ART-CHEM-BB B024294;2,5-dimethyl-3-pyrazolamine;2,5-dimethylpyrazol-3-amine;5-AMINO-1,3-DIMETHYLPYRAZOLE;1,3-Dimethyl-5-amino-pyrazole;3-diMethyl-1H-pyrazol-5-aMine
CBNumber
CB4196460
Molecular Formula
C5H9N3
Formula Weight
111.15
MOL File
3524-32-1.mol
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1,3-Dimethyl-1H-pyrazol-5-amine Property

Melting point:
65-69 °C (lit.)
Boiling point:
121-123 °C(Press: 9 Torr)
Density 
1.17±0.1 g/cm3(Predicted)
Flash point:
88 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
crystalline powder
pka
4?+-.0.10(Predicted)
color 
Light orange
Sensitive 
Hygroscopic
BRN 
113420
InChI
InChI=1S/C5H9N3/c1-4-3-5(6)8(2)7-4/h3H,6H2,1-2H3
InChIKey
ZFDGMMZLXSFNFU-UHFFFAOYSA-N
SMILES
N1(C)C(N)=CC(C)=N1
CAS DataBase Reference
3524-32-1(CAS DataBase Reference)
NIST Chemistry Reference
5-Amino-1,3-dimethylpyrazole(3524-32-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
532223
Product name
5-Amino-1,3-dimethylpyrazole
Purity
97%
Packaging
10g
Price
$192
Updated
2025/07/31
TCI Chemical
Product number
A3464
Product name
1,3-Dimethyl-1H-pyrazol-5-amine
Purity
min. 98.0 %
Packaging
5G
Price
$75
Updated
2025/07/31
TCI Chemical
Product number
A3464
Product name
1,3-Dimethyl-1H-pyrazol-5-amine
Purity
min. 98.0 %
Packaging
25G
Price
$224
Updated
2025/07/31
TRC
Product number
A607440
Product name
5-Amino-1,3-dimethylpyrazole
Packaging
10g
Price
$415
Updated
2021/12/16
Usbiological
Product number
A1377-38
Product name
5-Amino-1,3-dimethylpyrazole
Packaging
5g
Price
$1832
Updated
2021/12/16
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1,3-Dimethyl-1H-pyrazol-5-amine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

5-Amino-1,3-dimethylpyrazole may be used in the preparation of:

  • 5-benzamido-1,3-dimethylpyrazole
  • diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylene}malonate
  • 5-amino-1,3-dimethyl-4-phthalidylpyrazole
  • (E)-N-(3,7-dimethylocta-2,6-dienyl)-1,3-dimethyl-1H-pyrazol-5-amine analog(LQFM002)
  • 4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-ol

General Description

5-Amino-1,3-dimethylpyrazole undergoes cyclocondensation with ethyl acetoacetate to form the corresponding tetrahydropyrazolopyridine derivatives.

Synthesis

1118-61-2

60-34-4

3524-32-1

To a solution of 3-aminobut-2-enenenitrile (16.5 g, 0.2 mol) in n-pentanol (40 mL) was slowly added methylhydrazine (12.9 g, 0.28 mol). The reaction mixture was heated to reflux and kept for 3 hours. Upon completion of the reaction, n-pentanol and excess methylhydrazine were removed by distillation under reduced pressure. The resulting beige precipitate was dissolved in heptane (150 mL) and filtered through a sintered funnel. The filtrate was dried under vacuum at 40 °C to afford 5-amino-1,3-dimethylpyrazole as a beige solid (13.5 g, 60.4% yield).

References

[1] Patent: WO2012/92880, 2012, A1. Location in patent: Page/Page column 59
[2] Journal of the American Chemical Society, 1959, vol. 81, p. 2452,2455
[3] Patent: US6338741, 2002, B1. Location in patent: Page column 15
[4] Journal of Combinatorial Chemistry, 2010, vol. 12, # 4, p. 510 - 517

1,3-Dimethyl-1H-pyrazol-5-amine Preparation Products And Raw materials

Raw materials

Sodium azide Ethanol Acetone Diethyl oxalate Sodium Sulfuryl chloride 1-Pentanol Ethyl acetate Methylhydrazine sulfate Hydrochloric acid 3-Aminocrotononitrile Dichloromethane Methylhydrazine Sodium hydroxide Isopropyl alcohol Thionyl chloride Sulfuric acid

Preparation Products

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View Lastest Price from 1,3-Dimethyl-1H-pyrazol-5-amine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
1,3-Dimethyl-1H-pyrazol-5-amine 3524-32-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-31
Hebei Chuanghai Biotechnology Co., Ltd
Product
1,3-Dimethyl-1H-pyrazol-5-amine 3524-32-1
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-13
Career Henan Chemical Co
Product
1,3-Dimethyl-1H-pyrazol-5-amine 3524-32-1
Price
US $2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customise
Release date
2018-08-09

3524-32-1, 1,3-Dimethyl-1H-pyrazol-5-amineRelated Search:

5-AMINO-4-CYANO-3-CYANOMETHYL-1-PHENYLPYRAZOLE 4,7-DIMETHYLPYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXYLIC ACID 1,3-Dimethyl-1H-pyrazol-5-amine 5-AMINO-1-METHYL-3-PHENYLPYRAZOLE 5-Amino-3-methyl-1-phenylpyrazole 4,7-DIMETHYLPYRAZOLO[5,1-C][1,2,4]TRIAZINE-3-CARBOXYLIC ACID 3-AMINO-1,5-DIMETHYLPYRAZOLE 3,4-Dimethyl-1-H-pyrazol-5-amine,4,5-DIMETHYL-1H-PYRAZOL-3-AMINE 1,5-Dimethyl-1H-pyrazol-3-ylamine ,97%,1,5-DIMETHYL-1 H-PYRAZOL-3-YLAMINE,1,5-DIMETHYL-1H-PYRAZOL-3-AMINE 1,3-Dimethylpyrazole 2-(3-CHLORO-PHENYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE 5-AMINO-3-METHYL-1-P-TOLYLPYRAZOLE ETHYL 2-METHYL-7-OXO-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE ETHYL 7-METHYL-2-PHENYLPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE 3-CYCLOPROPYL-1-PHENYL-1H-PYRAZOL-5-AMINE 1-(4,7-DIMETHYLPYRAZOLO[5,1-C][1,2,4]TRIAZIN-3-YL)ETHAN-1-ONE ETHYL 2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE 5-HYDRAZINO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE

  • BUTTPARK 29\04-74
  • ART-CHEM-BB B024294
  • AKOS B024294
  • AKOS PAO-1219
  • AKOS BBS-00004675
  • 5-AMINO-1,3-DIMETHYLPYRAZOLE
  • 3-AMINO-2,5-DIMETHYL-2H-PYRAZOLE
  • 2,5-DIMETHYL-2H-PYRAZOL-3-YLAMINE
  • 1,3-DIMETHYL-1H-PYRAZOL-5-AMINE
  • 1,3-Dimethyl-1H-pyrazol-5-ylamine
  • 1,3-Dimethyl-5-amino-pyrazole
  • 1,3-dimethyl-1H-pyrazol-5-amine(SALTDATA: FREE)
  • 3-diMethyl-1H-pyrazol-5-aMine
  • 5-Amino-1,3-dimethyl-1H-pyrazole
  • 1,3-Dimethyl-1H-pyrazole-5-amine ,97%
  • 1,3-Dimethyl-1H-pyrazole-5-amine
  • 5-Amino-1,3-dimethylpyrazole 97%
  • (2,5-dimethylpyrazol-3-yl)amine
  • 2,5-dimethyl-3-pyrazolamine
  • 2,5-dimethylpyrazol-3-amine
  • 1H-Pyrazol-5-amine,1,3-dimethyl-
  • 1,3-Dimethyl-1H-pyrazole-5yl-amine
  • 5-Amino-1,3-dimethylpyrazole?New
  • 3524-32-1
  • Pyrazoles
  • Heterocyclic Building Blocks
  • Heterocycle
  • Building Blocks
  • C3 to C5
  • Chemical Synthesis
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrazoles