ChemicalBook > CAS DataBase List > 5-Fluoroisatin

5-Fluoroisatin

Product Name
5-Fluoroisatin
CAS No.
443-69-6
Chemical Name
5-Fluoroisatin
Synonyms
5-FLUOROINDOLINE-2,3-DIONE;Fluoroisatin;5-FLUORO-1H-INDOLE-2,3-DIONE;NSC 39161;uoroisatin;5-Fluorosatin;5-FLUOROISATIN;5-FLUOROISATINE;5- fluoroindigo;Compound Fr13755
CBNumber
CB4206497
Molecular Formula
C8H4FNO2
Formula Weight
165.12
MOL File
443-69-6.mol
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5-Fluoroisatin Property

Melting point:
224-227 °C (lit.)
Density 
1.477±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, DMSO, Methanol
pka
8.51±0.20(Predicted)
form 
Powder
color 
Red
BRN 
131241
InChIKey
GKODDAXOSGGARJ-UHFFFAOYSA-N
CAS DataBase Reference
443-69-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29337900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
366978
Product name
5-Fluoroisatin
Purity
98%
Packaging
5g
Price
$53.2
Updated
2024/03/01
TCI Chemical
Product number
F0589
Product name
5-Fluoroisatin
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$39
Updated
2024/03/01
TCI Chemical
Product number
F0589
Product name
5-Fluoroisatin
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$112
Updated
2024/03/01
Alfa Aesar
Product number
B20831
Product name
5-Fluoroisatin, 98%
Packaging
1g
Price
$19.65
Updated
2024/03/01
Alfa Aesar
Product number
B20831
Product name
5-Fluoroisatin, 98%
Packaging
5g
Price
$59.65
Updated
2024/03/01
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5-Fluoroisatin Chemical Properties,Usage,Production

Chemical Properties

red Crystalline Powder

Uses

Reactant for preparation of:

  • Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds
  • Potential antimycobacterial agents
  • Inhibitors of c-Met kinase
  • Inhibitors of TAK1 kinase
  • Herpes simplex virus inhibitors
  • IKKβ inhibitors
  • Inhibitors of vitiligo disease
  • Potential drug candidates with anti-HIV activity and anti-tubercular activity

Uses

It showed antibacterial and antifungal activities.

Definition

ChEBI: 5-Fluoroisatin is a member of indoles. It has a role as an anticoronaviral agent.

General Description

5-Fluoroisatin has been reported as the precursor of the Sunitinib (Sutent) drug. 5-Fluoroisatin has been approved by the Food and Drugs Administration (FDA) in 2006 for the treatment of renal cell carcinoma (RCC) and gastrointestinal stromal tumor (GIST).

5-Fluoroisatin Preparation Products And Raw materials

Raw materials

Preparation Products

Flumazenil
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5-Fluoroisatin Suppliers

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Hotechem Shanghai Co., Ltd.,
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View Lastest Price from 5-Fluoroisatin manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
5-Fluoroisatin 443-69-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08
Career Henan Chemical Co
Product
5-Fluoroisatin 443-69-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-23

443-69-6, 5-Fluoroisatin Related Search:

Isatin Indole-3-acetic acid Dehydroepiandrosterone 5-Fluoroindole Isophorone 5-Fluoro-2-oxindole Isatoic Anhydride cis-Octahydroisoindole 6-Chloro-5-fluoroindole Indirubin Indometacin Naringin dihydrochalcone Indole-3-butyric acid 1-(2,6-Dichlorophenyl)indolin-2-one 5,6-DIFLUOROISATIN 5-FLUORO-6-CHLORO ISATIN 6-Fluoroisatoic anhydride 5-Fluoro-7-Methyl Isatin

  • BUTTPARK 24\07-36
  • AKOS BBS-00006537
  • 5-FLUOROINDOLINE-2,3-DIONE
  • 5-FLUOROISATIN
  • 5-FLUOROISATINE
  • 5-FLUOROINDOLE-2,3-DIONE
  • 5-FLUORO-1H-INDOLE-2,3-DIONE
  • 5-Fluoroisatin,98%
  • 5-Fluoroisatin 97%
  • 5-FLUOROISATIN OR 5-FLUORO-1H-INDOLE-2,3-DIONE
  • 5-Fluoroisatin97%
  • 1H-Indole-2,3-dione, 5-fluoro-
  • 5-FLUORO ISATINIC ANHYDRIDE
  • 5-FLUOROISATIN 99+%
  • 5-Fluoro-2,3-indoledione
  • NSC 39161
  • 5-Fluorosatin
  • 5-fluoro-1H-indole-2,3-dione(SALTDATA: FREE)
  • Fluoroisatin
  • 5-Fluoroisatin, 98% 5GR
  • 5-Fluoroindoline-2,3-dione, 5-Fluoro-1H-indole-2,3-dione
  • uoroisatin
  • Sunitinib Impurity 32
  • 5-Fluoroisatin&gt
  • 5-Fluoro-2,3-indolinedione
  • 5-Fluoroisatin ISO 9001：2015 REACH
  • Sunitinib Impurity 46
  • 4,5,9,14-Pyrenetetrone
  • 1-Heptanol,12-amino-
  • 5- fluoroindigo
  • Compound Fr13755
  • 5-Fluoroisatin(5-Fluoro-1H-indole-2,3-dione)
  • 5-Fluorosatin in isooctane
  • 443-69-6
  • 433-69-6
  • 443-69-9
  • C8H4FNO2
  • Building Blocks
  • AMIDE
  • Heterocyclic Building Blocks
  • Indoles
  • Fluorinated heterocyclic series
  • Heterocyclic Building Blocks
  • blocks
  • IndolesOxindoles
  • Indole/indoline/oxindole
  • Indole and Indoline
  • Indane/Indanone and Derivatives
  • Isatin series
  • Simple Indoles
  • Sunitinib
  • Heterocyclic Compounds
  • Indoles
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Boronic Acid
  • Building Blocks