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Aurora Kinase Inhibitor III

Product Name
Aurora Kinase Inhibitor III
CAS No.
879127-16-9
Chemical Name
Aurora Kinase Inhibitor III
Synonyms
AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
CBNumber
CB42098016
Molecular Formula
C21H18F3N5O
Formula Weight
413.4
MOL File
879127-16-9.mol
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Aurora Kinase Inhibitor III Property

Density 
1.456±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: <2mg/mL
pka
14.51±0.70(Predicted)
form 
White solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21851
Product name
Aurora Kinase Inhibitor III
Purity
≥98%
Packaging
500μg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
21851
Product name
Aurora Kinase Inhibitor III
Purity
≥98%
Packaging
1mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
21851
Product name
Aurora Kinase Inhibitor III
Purity
≥98%
Packaging
5mg
Price
$570
Updated
2024/03/01
Biorbyt Ltd
Product number
orb611996
Product name
Aurora Kinase Inhibitor III
Purity
>98%
Packaging
250mg
Price
$1654.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611996
Product name
Aurora Kinase Inhibitor III
Purity
>98%
Packaging
1g
Price
$3282.7
Updated
2021/12/16
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Aurora Kinase Inhibitor III Chemical Properties,Usage,Production

General Description

A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC50 = 131, 386, 591, and 887 nM, respectively).

Biochem/physiol Actions

Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively

Aurora Kinase Inhibitor III Preparation Products And Raw materials

Raw materials

Preparation Products

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Aurora Kinase Inhibitor III Suppliers

China 40 Switzerland 1 United States 5 Global 46
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9737
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4153
Advantage
55
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
993
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8013
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2985
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1836
Advantage
55
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4979
Advantage
55
Heze Development Zone chuangli Chemical Co., Ltd.
Tel
+86-530-529 6766，+86-15666160102 15666160102
Fax
0530-529 6766
Email
info@chuangli-chem.com
Country
China
ProdList
874
Advantage
55
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20522
Advantage
60

879127-16-9, Aurora Kinase Inhibitor IIIRelated Search:


  • Aurora Kinase Inhibitor III
  • Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
  • N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
  • AKI-7169
  • Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem
  • Aurora Kinase Inhibitor 3
  • Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-
  • Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide >=98% (HPLC), solid
  • AKI-7169(Aurora Kinase Inhibitor III)
  • N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide
  • Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
  • 879127-16-9