ChemicalBook > CAS DataBase List > Aurora Kinase Inhibitor III
Aurora Kinase Inhibitor III
- Product Name
- Aurora Kinase Inhibitor III
- CAS No.
- 879127-16-9
- Chemical Name
- Aurora Kinase Inhibitor III
- Synonyms
- AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
- CBNumber
- CB42098016
- Molecular Formula
- C21H18F3N5O
- Formula Weight
- 413.4
- MOL File
- 879127-16-9.mol
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Aurora Kinase Inhibitor III Property
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: <2mg/mL
- pka
- 14.51±0.70(Predicted)
- form
- White solid
- color
- white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21851
- Product name
- Aurora Kinase Inhibitor III
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21851
- Product name
- Aurora Kinase Inhibitor III
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $130
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21851
- Product name
- Aurora Kinase Inhibitor III
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $570
- Updated
- 2024/03/01
Biorbyt Ltd
- Product number
- orb611996
- Product name
- Aurora Kinase Inhibitor III
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1654.1
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611996
- Product name
- Aurora Kinase Inhibitor III
- Purity
- >98%
- Packaging
- 1g
- Price
- $3282.7
- Updated
- 2021/12/16
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Aurora Kinase Inhibitor III Chemical Properties,Usage,Production
General Description
A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC50 = 131, 386, 591, and 887 nM, respectively).
Biochem/physiol Actions
Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively
Aurora Kinase Inhibitor III Preparation Products And Raw materials
Raw materials
Preparation Products
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