Aurora Kinase Inhibitor III

Product Name: Aurora Kinase Inhibitor III
CAS No.: 879127-16-9
Chemical Name: Aurora Kinase Inhibitor III
Synonyms: AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
CBNumber: CB42098016
Molecular Formula: C21H18F3N5O
Formula Weight: 413.4
MOL File: 879127-16-9.mol

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Aurora Kinase Inhibitor III Property

Density: 1.456±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H2O: <2mg/mL
pka: 14.51±0.70(Predicted)
form: White solid
color: white
Water Solubility: H2O: <2mg/mL
DMSO: >7mg/mL

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21851
Product name: Aurora Kinase Inhibitor III
Purity: ≥98%
Packaging: 500μg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 21851
Product name: Aurora Kinase Inhibitor III
Purity: ≥98%
Packaging: 1mg
Price: $130
Updated: 2024/03/01

Cayman Chemical

Product number: 21851
Product name: Aurora Kinase Inhibitor III
Purity: ≥98%
Packaging: 5mg
Price: $570
Updated: 2024/03/01

ChemScene

Product number: CS-0045304
Product name: AuroraKinaseInhibitor3
Purity: 98.98%
Packaging: 1mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-0045304
Product name: AuroraKinaseInhibitor3
Purity: 98.98%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

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Aurora Kinase Inhibitor III Chemical Properties,Usage,Production

General Description

A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC₅₀ = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC₅₀ = 131, 386, 591, and 887 nM, respectively).

Biochem/physiol Actions

Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively

Aurora Kinase Inhibitor III Preparation Products And Raw materials

Raw materials

Preparation Products

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Aurora Kinase Inhibitor III Suppliers

China 44 Switzerland 1 United States 6 Global 51

Sigma-Aldrich

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879127-16-9, Aurora Kinase Inhibitor IIIRelated Search:

Aurora Kinase Inhibitor III

Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide

N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide

AKI-7169

Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem

Aurora Kinase Inhibitor 3

Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-

Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide >=98% (HPLC), solid

AKI-7169(Aurora Kinase Inhibitor III)

N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide

Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit

879127-16-9