ChemicalBook > CAS DataBase List > Aurora Kinase Inhibitor III

Aurora Kinase Inhibitor III

Product Name
Aurora Kinase Inhibitor III
CAS No.
879127-16-9
Chemical Name
Aurora Kinase Inhibitor III
Synonyms
AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
CBNumber
CB42098016
Molecular Formula
C21H18F3N5O
Formula Weight
413.4
MOL File
879127-16-9.mol
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Aurora Kinase Inhibitor III Property

Density 
1.456±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: <2mg/mL
pka
14.51±0.70(Predicted)
form 
White solid
color 
white
Water Solubility 
H2O: <2mg/mL
DMSO: >7mg/mL
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21851
Product name
Aurora Kinase Inhibitor III
Purity
≥98%
Packaging
500μg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
21851
Product name
Aurora Kinase Inhibitor III
Purity
≥98%
Packaging
1mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
21851
Product name
Aurora Kinase Inhibitor III
Purity
≥98%
Packaging
5mg
Price
$570
Updated
2024/03/01
ChemScene
Product number
CS-0045304
Product name
AuroraKinaseInhibitor3
Purity
98.98%
Packaging
1mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0045304
Product name
AuroraKinaseInhibitor3
Purity
98.98%
Packaging
5mg
Price
$350
Updated
2021/12/16
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Aurora Kinase Inhibitor III Chemical Properties,Usage,Production

General Description

A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC50 = 131, 386, 591, and 887 nM, respectively).

Biochem/physiol Actions

Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively

Aurora Kinase Inhibitor III Preparation Products And Raw materials

Raw materials

Preparation Products

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Aurora Kinase Inhibitor III Suppliers

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879127-16-9, Aurora Kinase Inhibitor IIIRelated Search:


  • Aurora Kinase Inhibitor III
  • Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
  • N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
  • AKI-7169
  • Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem
  • Aurora Kinase Inhibitor 3
  • Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-
  • Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide >=98% (HPLC), solid
  • AKI-7169(Aurora Kinase Inhibitor III)
  • N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide
  • Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
  • 879127-16-9