ChemicalBook > CAS DataBase List > 2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide

2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide

Product Name
2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide
CAS No.
412950-08-4
Chemical Name
2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide
Synonyms
Rilapladib;GTPL7376;GTPL 7376;Sb 659032;GTPL-7376;Unii-o14cwe893z;Rilapladib (SB 659032);Rilapladib, 10 mM in DMSO;2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide;1(4H)-Quinolineacetamide, 2-[[(2,3-difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-
CBNumber
CB42128751
Molecular Formula
C40H38F5N3O3S
Formula Weight
735.8
MOL File
412950-08-4.mol
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2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide Property

Boiling point:
768.6±60.0 °C(Predicted)
Density 
1.36
storage temp. 
Store at -20°C
solubility 
DMSO : 86.67 mg/mL (117.79 mM);Water : < 0.1 mg/mL (insoluble)
pka
7.93±0.20(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
43593
Product name
Rilapladib
Purity
≥95%
Packaging
5mg
Price
$303
Updated
2026/04/30
Cayman Chemical
Product number
43593
Product name
Rilapladib
Purity
≥95%
Packaging
10mg
Price
$515
Updated
2026/04/30
Cayman Chemical
Product number
43593
Product name
Rilapladib
Purity
≥95%
Packaging
25mg
Price
$757
Updated
2026/04/30
aablocks
Product number
AA00CL7R
Product name
Rilapladib
Packaging
1mg
Price
$96
Updated
2026/05/28
aablocks
Product number
AA00CL7R
Product name
Rilapladib
Packaging
5mg
Price
$212
Updated
2026/05/28
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2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide Chemical Properties,Usage,Production

Uses

Treatment of atherosclerosis.

2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide Suppliers

Shanghai Fuhe Chemistry Technology Co., Ltd.
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China
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0371-55932928 18937192232
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696,15000506266 15000506266
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ShangHai Biochempartner Co.,Ltd
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Shanghai Chaolan Chemical Technology Center
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Amadis Chemical Company Limited
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Wellman Pharmaceutical Group Limited
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15807197853 18971451745
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Shanghai Biopharmaleader Co., Ltd.
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412950-08-4, 2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamideRelated Search:


  • 2-[[(2,3-Difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1(4H)-quinolineacetamide
  • Sb 659032
  • Unii-o14cwe893z
  • 1(4H)-Quinolineacetamide, 2-[[(2,3-difluorophenyl)methyl]thio]-N-[1-(2-methoxyethyl)-4-piperidinyl]-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-
  • GTPL 7376
  • GTPL7376
  • GTPL-7376
  • Rilapladib (SB 659032)
  • Rilapladib, 10 mM in DMSO
  • Rilapladib
  • 412950-08-4
  • C40H38F5N3O3S