FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

Product Name: FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
CAS No.: 97612-24-3
Chemical Name: FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
Synonyms: Eticlopride HCl;Eticlopride hydrochl;S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE;(2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride;3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride;Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1);FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
CBNumber: CB42130556
Molecular Formula: C17H26Cl2N2O3
Formula Weight: 377.31
MOL File: 97612-24-3.mol

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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Property

Melting point:: 144-146 °C(Solv: acetone (67-64-1))
storage temp.: Desiccate at RT
solubility: H2O: soluble >10mg/mL
form: powder
color: off-white
optical activity: [α]27/D 7.2°, c = 0.3 in methanol(lit.)
Water Solubility: Soluble to 100 mM in water

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Safety

WGK Germany: 3
RTECS: CV2450000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E101
Product name: S-(?)-Eticlopride hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $178
Updated: 2024/03/01

Sigma-Aldrich

Product number: E101
Product name: S-(?)-Eticlopride hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 100mg
Price: $476
Updated: 2024/03/01

Cayman Chemical

Product number: 29112
Product name: Eticlopride (hydrochloride)
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 29112
Product name: Eticlopride (hydrochloride)
Packaging: 10mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 29112
Product name: Eticlopride (hydrochloride)
Packaging: 25mg
Price: $252
Updated: 2024/03/01

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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Chemical Properties,Usage,Production

Uses

Dopamine receptor antagonist

Uses

S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments.

Biological Activity

Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic.

Biochem/physiol Actions

Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism.

storage

room temperature (desiccate)

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Suppliers

China 16 India 1 United Kingdom 1 United States 7 Global 25

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Sigma-Aldrich

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97612-24-3, FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochlorideRelated Search:

Etidronate disodium S(-)-ETICLOPRIDE HYDROCHLORIDE

S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride

Eticlopride hydrochl

Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1)

(2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride

Eticlopride HCl

97612-24-3