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5-methyl-1H-pyrazole-3-carbaldehyde

Product Name
5-methyl-1H-pyrazole-3-carbaldehyde
CAS No.
3273-44-7
Chemical Name
5-methyl-1H-pyrazole-3-carbaldehyde
Synonyms
5-Methyl-3-forMylpyrazole;3-ForMyl-5-Methylpyrazole;5-Methylpyrazole-3-carbaldehyde;5-methyl-1H-pyrazole-3-carbaldehyde;5-Methyl-1H-pyrazole-3-carboxaldehyde;1H-Pyrazole-3-carboxaldehyde, 5-methyl-;5-methyl-1H-pyrazole-3-carbaldehyde(SALTDATA: FREE);3-methyl-1H-pyrazole-5-carbaldehyde(SALTDATA: FREE)
CBNumber
CB42134059
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
3273-44-7.mol
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5-methyl-1H-pyrazole-3-carbaldehyde Property

Melting point:
190 °C
Boiling point:
294.2±20.0 °C(Predicted)
Density 
1.238±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
11.76±0.10(Predicted)
Appearance
Off-white to yellow Solid
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Safety

RIDADR 
UN2811
HazardClass 
IRRITANT
HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
M336415
Product name
5-Methyl-1H-pyrazole-3-carbaldehyde
Packaging
500mg
Price
$240
Updated
2021/12/16
Apolloscientific
Product number
OR925890
Product name
5-Methyl-1H-pyrazole-3-carbaldehyde
Purity
95%
Packaging
1g
Price
$355
Updated
2021/12/16
Matrix Scientific
Product number
016461
Product name
3-Methyl-1H-pyrazole-5-carbaldehyde
Packaging
2.500g
Price
$573
Updated
2021/12/16
Matrix Scientific
Product number
016461
Product name
3-Methyl-1H-pyrazole-5-carbaldehyde
Packaging
500mg
Price
$144
Updated
2021/12/16
Chemenu
Product number
CM112608
Product name
5-methyl-1H-pyrazole-3-carbaldehyde
Purity
95+%
Packaging
10g
Price
$739
Updated
2021/12/16
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5-methyl-1H-pyrazole-3-carbaldehyde Chemical Properties,Usage,Production

Synthesis

4027-57-0

3273-44-7

General procedure for the synthesis of 5-methyl-1H-pyrazole-3-carbaldehyde from ethyl 3-methylpyrazole-5-carboxylate: 3-ethoxycarbonyl-5-methylpyrazole (1.0 g, 4.34 mmol) was dissolved in 15 ml of purified toluene under the protection of nitrogen, diisobutylaluminum hydride (DIBAL, 8.68 ml, 8.62 mmol) was added slowly and the reaction was carried out at -78 C. The reaction was stirred. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio hexane: ethyl acetate = 6:1). Upon completion of the reaction, the reaction was quenched by slow addition of methanol and water and the resulting mixture was filtered through a bed of diatomaceous earth and the aqueous layer was extracted with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure. The concentrate was purified by column chromatography (eluent ratio of hexane: ethyl acetate: dichloromethane = 3:1:1) to afford the target product 5-methyl-1H-pyrazole-3-carbaldehyde in 82.4% yield. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 9.92 (s, 1H), 6.68 (s, 1H), 2.82 (s, 3H).

References

[1] Patent: EP1757590, 2007, A1. Location in patent: Page/Page column 5
[2] Patent: US2007/49604, 2007, A1. Location in patent: Page/Page column 3

5-methyl-1H-pyrazole-3-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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5-methyl-1H-pyrazole-3-carbaldehyde Suppliers

China 64 India 1 United States 5 Global 70
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 5-methyl-1H-pyrazole-3-carbaldehyde manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5-methyl-1H-pyrazole-3-carbaldehyde 3273-44-7
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Shaanxi Dideu Medichem Co. Ltd
Product
5-Methyl-1H-pyrazole-3-carbaldehyde 3273-44-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-11

3273-44-7, 5-methyl-1H-pyrazole-3-carbaldehydeRelated Search:

1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 3,5-PYRAZOLEDICARBOXYLIC ACID 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBONYL CHLORIDE 1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBONYL CHLORIDE 1,4-DIHYDRO-3-BETA-D-RIBOFURANOSYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE ETHYL 1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLATE Pyrazofurin Ethyl 3-methyl-1H-pyrazole-5-carboxylate 5-Methyl-1H-pyrazole-3-carboxylic acid 1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID 5-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE Ethyl 5-thien-2-yl-1H-pyrazole-3-carboxylate 1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBONYL CHLORIDE ETHYL 1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBOXYLATE 1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID ETHYL ESTER ETHYL 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLATE 1-ETHYL-3-METHYL-1H-PYRAZOLE-5-CARBOHYDRAZIDE PYRAZOLE-3,5-DICARBOXYLIC ACID, MONOPOTASSIUM SALT

  • 5-methyl-1H-pyrazole-3-carbaldehyde
  • 3-methyl-1H-pyrazole-5-carbaldehyde(SALTDATA: FREE)
  • 5-methyl-1H-pyrazole-3-carbaldehyde(SALTDATA: FREE)
  • 5-Methyl-1H-pyrazole-3-carboxaldehyde
  • 3-ForMyl-5-Methylpyrazole
  • 5-Methyl-3-forMylpyrazole
  • 5-Methylpyrazole-3-carbaldehyde
  • 1H-Pyrazole-3-carboxaldehyde, 5-methyl-
  • 3273-44-7