2-Isopropyl-N,2,3-trimethylbutyramide
- Product Name
- 2-Isopropyl-N,2,3-trimethylbutyramide
- CAS No.
- 51115-67-4
- Chemical Name
- 2-Isopropyl-N,2,3-trimethylbutyramide
- Synonyms
- WS-23;2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE;N,2,3-Trimethyl-2-propan-2-ylbutanamide;FEMA 3804;Trimethyl Isopropyl Butanamide;2-Isopropyl-N,2,3-trimethylbutanamide;N,2,3-Trimethyl-2-isopropylbutanamide,WS-23;3-trimethylbutyramide;methyldiisopropylpropionamide;N,2,3-TRIMETHYL-2-ISOPROPYLBUTANAMIDE
- CBNumber
- CB4227036
- Molecular Formula
- C10H21NO
- Formula Weight
- 171.28
- MOL File
- 51115-67-4.mol
2-Isopropyl-N,2,3-trimethylbutyramide Property
- Melting point:
- 58-61 °C
- Boiling point:
- bp0.35mm 83-85°
- Density
- 0.9419 (rough estimate)
- vapor pressure
- 0.3-0.32Pa at 25℃
- refractive index
- 1.4621 (estimate)
- FEMA
- 3804 | 2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 16.46±0.46(Predicted)
- form
- Solid
- color
- White to Almost white
- Odor
- at 25.00 % in dipropylene glycol. mild cooling mentholic minty
- Odor Type
- minty
- JECFA Number
- 1595
- Merck
- 14,9716
- LogP
- 2.5 at 25℃ and pH7
- CAS DataBase Reference
- 51115-67-4(CAS DataBase Reference)
- EPA Substance Registry System
- Butanamide, N,2,3-trimethyl-2-(1-methylethyl)- (51115-67-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-52/53
- Safety Statements
- 37/39-26
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- I0729
- Product name
- 2-Isopropyl-N,2,3-trimethylbutyramide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $24
- Updated
- 2024/03/01
- Product number
- I0729
- Product name
- 2-Isopropyl-N,2,3-trimethylbutyramide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $65
- Updated
- 2024/03/01
- Product number
- I872698
- Product name
- 2-Isopropyl-N,2,3-trimethylbutanamide
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM0078886
- Product name
- N,2,3-TRIMETHYL-2-ISOPROPYLBUTAMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $866.75
- Updated
- 2021/12/16
- Product number
- 35040
- Product name
- 2-Isopropyl-N,2,3-trimethylbutyramide,99.5-100.0%(GC),meetsFGspecifications,KOSHER,FEMA3804
- Purity
- 99.5-100.0%(GC)
- Packaging
- 5G
- Price
- $29.12
- Updated
- 2021/12/16
2-Isopropyl-N,2,3-trimethylbutyramide Chemical Properties,Usage,Production
Description
2-isopropyl-N,2,3-trimethylbutyramide is one nearly odorless white crystalline powder widely used as a coolant in medicinal preparations, oral care products, foodstuffs, cosmetics, and confection-eye products. It is an artificial synthesis cooling agent and could be synthesized by the Ritter reaction of 2,2-diisopropylpropionitrile (DIPPN) with methanol in the presence of acid. Compared with menthol, WS-23 is characterized by a continuous and long-lasting cooling and refreshing effect with no side effects of burning or stinging sensations. As an important additive in menthol cigarettes, WS-23 can cover up the bitter and astringent taste of cigarettes, make the cigarette feel fresh, improve the coordination and softness of cigarette smoke, and reduce the thorn in the mouth and throat. WS-23 is also compatible with other flavors and cooling agents[1].
Chemical Properties
N,2,3-Trimethyl-2-isopropylbutanamide is a white, crystalline powder,which gives a physiological
cooling sensation on skin or mucosa. It is mainly used to create cooling
and freshness in oral care preparations.
The material can be prepared by a Ritter reaction using N,2,3-trimethyl-2-
isopropylbutyronitrile as the starting material and alkylating agents such as, for
example, borates, carbonates, or phosphates.
Chemical Properties
2-Isopropyl-N-2,3-trimethylbutyramide has a cool, mint–menthol-type odor
Uses
2-Isopropyl-N,2,3-trimethylbutanamide is flavored compound and comprising the recount flavored compound for electronic cigarette liquid.
Uses
Physiological coolant in foods, beverages, tobacco products, toiletries, cosmetics and pharmaceuticals.
Definition
ChEBI: N,2,3-Trimethyl-2-(1-methylethyl)butanamide is a fatty amide.
Aroma threshold values
Aroma characteristics at 5.0%: slight cooling impact with little character.
Taste threshold values
Taste characteristics at 20 ppm: high-impacting cooling that lasts on the tongue and palate.
Trade name
Winsense WS-23 (Renessenz).
References
[1] Ze-Hong Wu. “Acute and subacute inhalation toxicity assessment of WS-23 in Sprague-Dawley rats.” Journal of Applied Toxicology (2021): 1826–1838.
2-Isopropyl-N,2,3-trimethylbutyramide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Isopropyl-N,2,3-trimethylbutyramide manufacturers
- Product
- Cooling Agent Ws-23 51115-67-4
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-08
- Product
- 2-Isopropyl-N,2,3-trimethylbutyramide 51115-67-4
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-05-31
- Product
- N,2,3-Trimethyl-2-isopropylbutamide 51115-67-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2023-12-23