2-Isopropyl-N,2,3-trimethylbutyramide

ChemicalBook > CAS DataBase List > 2-Isopropyl-N,2,3-trimethylbutyramide

2-Isopropyl-N,2,3-trimethylbutyramide

Product Name: 2-Isopropyl-N,2,3-trimethylbutyramide
CAS No.: 51115-67-4
Chemical Name: 2-Isopropyl-N,2,3-trimethylbutyramide
Synonyms: WS-23;2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE;N,2,3-Trimethyl-2-propan-2-ylbutanamide;FEMA 3804;Trimethyl Isopropyl Butanamide;2-Isopropyl-N,2,3-trimethylbutanamide;N,2,3-Trimethyl-2-isopropylbutanamide,WS-23;3-trimethylbutyramide;methyldiisopropylpropionamide;N,2,3-TRIMETHYL-2-ISOPROPYLBUTANAMIDE
CBNumber: CB4227036
Molecular Formula: C10H21NO
Formula Weight: 171.28
MOL File: 51115-67-4.mol

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2-Isopropyl-N,2,3-trimethylbutyramide Property

Melting point:: 58-61 °C
Boiling point:: bp0.35mm 83-85°
Density: 0.9419 (rough estimate)
vapor pressure: 0.3-0.32Pa at 25℃
refractive index: 1.4621 (estimate)
FEMA: 3804 | 2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE
storage temp.: Sealed in dry,Room Temperature
form: Solid
pka: 16.46±0.46(Predicted)
color: White to Almost white
Odor: at 25.00 % in dipropylene glycol. mild cooling mentholic minty
Odor Type: minty
JECFA Number: 1595
Merck: 14,9716
LogP: 2.5 at 25℃ and pH7
CAS DataBase Reference: 51115-67-4(CAS DataBase Reference)
EPA Substance Registry System: Butanamide, N,2,3-trimethyl-2-(1-methylethyl)- (51115-67-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-52/53
Safety Statements: 37/39-26
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0729
Product name: 2-Isopropyl-N,2,3-trimethylbutyramide
Purity: >98.0%(GC)
Packaging: 5g
Price: $24
Updated: 2024/03/01

TCI Chemical

Product number: I0729
Product name: 2-Isopropyl-N,2,3-trimethylbutyramide
Purity: >98.0%(GC)
Packaging: 25g
Price: $65
Updated: 2024/03/01

TRC

Product number: I872698
Product name: 2-Isopropyl-N,2,3-trimethylbutanamide
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Chem-Impex

Product number: 35040
Product name: 2-Isopropyl-N,2,3-trimethylbutyramide,99.5-100.0%(GC),meetsFGspecifications,KOSHER,FEMA3804
Purity: 99.5-100.0%(GC)
Packaging: 5G
Price: $29.12
Updated: 2021/12/16

AK Scientific

Product number: 7087AB
Product name: 2-Isopropyl-N,2,3-trimethylbutanamide
Packaging: 100g
Price: $116
Updated: 2021/12/16

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2-Isopropyl-N,2,3-trimethylbutyramide Chemical Properties,Usage,Production

Description

2-isopropyl-N,2,3-trimethylbutyramide is one nearly odorless white crystalline powder widely used as a coolant in medicinal preparations, oral care products, foodstuffs, cosmetics, and confection-eye products. It is an artificial synthesis cooling agent and could be synthesized by the Ritter reaction of 2,2-diisopropylpropionitrile (DIPPN) with methanol in the presence of acid. Compared with menthol, WS-23 is characterized by a continuous and long-lasting cooling and refreshing effect with no side effects of burning or stinging sensations. As an important additive in menthol cigarettes, WS-23 can cover up the bitter and astringent taste of cigarettes, make the cigarette feel fresh, improve the coordination and softness of cigarette smoke, and reduce the thorn in the mouth and throat. WS-23 is also compatible with other flavors and cooling agents[1].

Chemical Properties

N,2,3-Trimethyl-2-isopropylbutanamide is a white, crystalline powder,which gives a physiological cooling sensation on skin or mucosa. It is mainly used to create cooling and freshness in oral care preparations.
The material can be prepared by a Ritter reaction using N,2,3-trimethyl-2- isopropylbutyronitrile as the starting material and alkylating agents such as, for example, borates, carbonates, or phosphates.

Chemical Properties

2-Isopropyl-N-2,3-trimethylbutyramide has a cool, mint–menthol-type odor

Uses

2-Isopropyl-N,2,3-trimethylbutanamide is flavored compound and comprising the recount flavored compound for electronic cigarette liquid.

Uses

Physiological coolant in foods, beverages, tobacco products, toiletries, cosmetics and pharmaceuticals.

Definition

ChEBI: N,2,3-Trimethyl-2-(1-methylethyl)butanamide is a fatty amide.

Aroma threshold values

Aroma characteristics at 5.0%: slight cooling impact with little character.

Taste threshold values

Taste characteristics at 20 ppm: high-impacting cooling that lasts on the tongue and palate.

Trade name

Winsense WS-23 (Renessenz).

References

[1] Ze-Hong Wu. “Acute and subacute inhalation toxicity assessment of WS-23 in Sprague-Dawley rats.” Journal of Applied Toxicology (2021): 1826–1838.

2-Isopropyl-N,2,3-trimethylbutyramide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Isopropyl-N,2,3-trimethylbutyramide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Cooling Agent Ws-23 51115-67-4
Price: US $120.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-08

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2-Isopropyl-N,2,3-trimethylbutyramide 51115-67-4
Price: US $70.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-05-31

Hebei Weibang Biotechnology Co., Ltd

Product: N,2,3-Trimethyl-2-isopropylbutamide 51115-67-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-01

51115-67-4, 2-Isopropyl-N,2,3-trimethylbutyramideRelated Search:

N,N-Dimethylacetamide N,N'-Methylenebisacrylamide N,N-Dimethylformamide Lauramidopropyl betaine Chloromethyl isopropyl carbonate Trimethyl borate Cocamidopropyl betaine 3-Methyl-2-butanone 4-Methoxybenzyl alcohol Butyramide 2-Butanone 18-dehydroxycytochalasin H 2-Isopropyl-N,2,3-trimethylbutyramide CHEMBRDG-BB 7805224 neosurugatoxin CBI-BB ZERO/004639 RARECHEM AQ TC 1047 CBI-BB ZERO/004818

FEMA 3804

N,2,3-Trimethyl-2-isopropylbutanamide,WS-23

2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE

N,2,3-TRIMETHYL-2-ISOPROPYLBUTAMIDE

N,2,3-TRIMETHYL-2-ISOPROPYLBUTANAMIDE

WS-23

methyldiisopropylpropionamide

2-Isopropyl-N,2,3-trimethylbutanamide

Cooling Agent Ws23

2-Isoprop

COOLER 23(WS-23)

coolkda ws-23

N,2,3-Trimethyl-2-isopropylbutamide WS-23

N,2,3-Trimethyl-2-(1-methylethyl)butanamide

Butanamide, N,2,3-trimethyl-2-(1-methylethyl)

N,2,3-Trimethyl-2-propan-2-ylbutanamide

N-Methyl-2,2-diisopropylpropanamide

Trimethyl Isopropyl Butanamide

Cooling agents ws-23 (N, 2,3- trimethyl-2-isopropyl butanamide)

2-Isopropyl-<i>N</i>,2,3-trimethylbutyramide

2-Isopropyl-N

3-trimethylbutyramide

Cooling agent ws-23 (N, 2,3- three -2- methyl isopropyl butyl amide)

2-Isopropyl-N,2,3-trimethylbutyramide&gt

-N,2,3-trimethyL

N,2,3-TRIMETHYL-2-ISOPROPYLBUTAMIDE 51115-67-4

N,2,3-Trimethyl-2-isopropylbutamide ISO 9001：2015 REACH

N,2,3-Trimethyl-2-isopropylbutamideCAS 51115-67-4

2-Isopropyl-N,2,3-trimethylbutyr ? ?amide(WS-23)

N,2,3- trimethyl -2- isopropyl butyramide

Benzyltrimethylammonium chloride 56-93-9

2-Isopropyl-N,2,3-trimethylbutanamide, 99.9%

WS-23,N,2,3-Trimethyl-2-isopropylbutamide

N,2,3-Trimethyl-2-isopropyl butyramide (WS-23)

51115-67-4

5115-67-4

9004-32-7

CH3CCHCH322CONHCH3