ChemicalBook > CAS DataBase List > (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

Product Name: (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
CAS No.: 56715-13-0
Chemical Name: (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE
Synonyms: (+)-Atenolol;(R)-(+)-ATENOLOL;Atenolol R-Isomer;(R)-(+)-AtenololHCl;(R)-(+)-Atenolol 99%;(R)-(+)-Atenolol;R(+)-ATENOLOL LESS ACTIVE ENANTIOME;Atenolol Impurity 15 ((R)-Atenolol);(R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide;2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
CBNumber: CB4230500
Molecular Formula: C14H22N2O3
Formula Weight: 266.34
MOL File: 56715-13-0.mol

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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Property

Melting point:: 148-152 °C(lit.)
Boiling point:: 508.0±50.0 °C(Predicted)
Density: 1.125±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >6.0 mg/mL
pka: 13.88±0.20(Predicted)
form: solid
color: pale yellow
optical activity: [α]25/D +16°, c = 1 in 1 M HCl
InChI: InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)/t12-/m1/s1
InChIKey: METKIMKYRPQLGS-GFCCVEGCSA-N
SMILES: C1(CC(N)=O)=CC=C(OC[C@H](O)CNC(C)C)C=C1

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 330884
Product name: (R)-(+)-Atenolol
Purity: 99%
Packaging: 100mg
Price: $160
Updated: 2024/03/01

Cayman Chemical

Product number: 18623
Product name: (R)-(+)-Atenolol
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 18623
Product name: (R)-(+)-Atenolol
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 18623
Product name: (R)-(+)-Atenolol
Purity: ≥98%
Packaging: 10mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 18623
Product name: (R)-(+)-Atenolol
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

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(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Chemical Properties,Usage,Production

Description

(+)-Atenolol is an enantiomer of the β₁-adrenergic receptor (β₁-AR) antagonist (±)-atenolol . (+)-Atenolol inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (K_i = 8.61 μM). Unlike (–)-atenolol and (±)-antenolol, (+)-atenolol has no effect on blood pressure in spontaneously hypertensive rats.

Uses

Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).

Uses

Antihypertensor

Uses

less active enantiomer

Definition

ChEBI: The (R)-enantiomer of atenolol.

IC 50

β adrenergic receptor

References

[1] stoschitzky k, egginger g, zernig g, et al. stereoselective features of (r)- and (s)-atenolol: clinical pharmacological, pharmacokinetic, and radioligand binding studies[j]. chirality, 1993, 5(1): 15-19.

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View Lastest Price from (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: (R)-Atenolol 56715-13-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-03-21

56715-13-0, (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDERelated Search:

S(-)-ATENOLOL (+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE Atenolol 4-Hydroxyphenylacetamide 4-METHOXYPHENYLACETAMIDE 1-AMINO-3-PHENOXY-PROPAN-2-OL 3-(4-methylphenoxy)propan-1-amine CHEMBRDG-BB 5482082 (2R)-(+)-1-AMINO-3-PHENOXY-2-PROPANOL AKOS BC-1949 4-(3-Amino-2-hydroxypropoxy)phenylacetamide 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL 1-AMINO-3-(4-ETHYLPHENOXY)PROPAN-2-OL (R)-3-ISOPROPYLAMINO-1,2-PROPANEDIOL 1-METHYLAMINO-3-PHENOXY-PROPAN-2-OL CHEMBRDG-BB 9070877 ATENOLOL IMPURITY STANDARD

(R)-(+)-AtenololHCl

4-[(R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide

2-[4-[(2R)-2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide

2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide

2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethanamide

(R)-(+)-Atenolol,(+)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide

R(+)-ATENOLOL LESS ACTIVE ENANTIOME

Benzeneacetamide, 4-[(2R)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-

Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, (R)-

(R)-(+)-ATENOLOL

4-[(2R)-2-Hydroxy-3-[(1-Methylethyl)aMino]propoxy]benzeneacetaMide

(R)-2-(4-(2-hydroxy-3-(isopropylaMino)propoxy)phenyl)acetaMide

Atenolol R-Isomer

(R)-(+)-Atenolol 99%

(+)-2-[4-[(2R)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy] phenyl] acetamide

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

(+)-Atenolol

Atenolol Impurity 15 ((R)-Atenolol)

Prenormin,2-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide

(<i>R</i>)-(+)-Atenolol

56715-13-0

CH32CHNHCH2CHOHCH2OC6H4CH2CONH2

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