4-METHOXYPHENYLACETAMIDE

Product Name: 4-METHOXYPHENYLACETAMIDE
CAS No.: 6343-93-7
Chemical Name: 4-METHOXYPHENYLACETAMIDE
Synonyms: Einecs 228-745-9;4-METHOXYPHENYLACETAMIDE;P-METHOXYPHENYLACETAMIDE;4-Methoxybenzeneacetamide;Benzeneacetamide, 4-methoxy-;PARA METHOXYPHENYL ACETAMIDE;PARA METHOXYL PHENYL ACETAMIDE;2-(4-METHOXY-PHENYL)-ACETAMIDE;2-hydroxybenzoic acid [(1R,3R,4S)-4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl] ester
CBNumber: CB6403610
Molecular Formula: C9H11NO2
Formula Weight: 165.19
MOL File: 6343-93-7.mol

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4-METHOXYPHENYLACETAMIDE Property

Melting point:: 182-184°C
Boiling point:: 354.7±25.0 °C(Predicted)
Density: 1.123±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 16.37±0.40(Predicted)
color: White to Off-White
BRN: 2088040
CAS DataBase Reference: 6343-93-7(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S580813
Product name: 2-(4-METHOXYPHENYL)ACETAMIDE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: S580813
Product name: 2-(4-METHOXYPHENYL)ACETAMIDE
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2024/03/01

TRC

Product number: M220175
Product name: 4-Methoxyphenylacetamide
Packaging: 100mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: 2762AL
Product name: 4-Methoxyphenylacetamide
Packaging: 1g
Price: $81
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0011947
Product name: 4-METHOXYPHENYLACETAMIDE
Purity: 95.00%
Packaging: 25G
Price: $1643.28
Updated: 2021/12/16

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4-METHOXYPHENYLACETAMIDE Chemical Properties,Usage,Production

Uses

4-Methoxyphenylacetamide is a useful reagent in the preparation of novel pyrrolidone-??based derivatives as potential p53-??MDM2 inhibitors for use as potential antitumor agents.

Synthesis

104-47-2

6343-93-7

General procedure for the synthesis of 4-methoxybenzeneacetamide from p-methoxybenzeneacetonitrile: Ni NPs/HT catalyst (0.05 g) was added to a thick-walled pressure tube, followed by water (4 ml) and p-methoxybenzeneacetonitrile (1 mmol). The reaction mixture was placed in an oil bath at 120 °C and stirred vigorously. The reaction process was monitored by TLC analysis. Upon completion of the reaction, the reaction mixture was extracted with ethyl acetate and subsequently filtered to remove the catalyst. The filtrate was cooled to 0 °C to allow white crystals to precipitate. The crystalline product was collected by simple filtration and dried under vacuum at room temperature to give analytically pure 4-methoxyphenylacetamide. If the product did not precipitate, the reaction mixture was extracted with ethyl acetate followed by purification by silica gel column chromatography to finally obtain 4-methoxyphenylacetamide.

References

[1] Synthesis, 1989, # 12, p. 949 - 951
[2] RSC Advances, 2015, vol. 5, # 9, p. 6365 - 6371
[3] Zeitschrift fur Chemie, 1980, vol. 20, # 10, p. 380 - 380
[4] Catalysis Communications, 2012, vol. 29, p. 109 - 113
[5] Green Chemistry, 2014, vol. 16, # 4, p. 2136 - 2141

4-METHOXYPHENYLACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-METHOXYPHENYLACETAMIDE Suppliers

China 51 Germany 2 India 3 Switzerland 1 United Kingdom 7 United States 12 Global 76

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6343-93-7, 4-METHOXYPHENYLACETAMIDERelated Search:

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE oxyphenisatine di(acetate) S(-)-ATENOLOL Atenolol (4-BUTOXYPHENYL)ACETAMIDE 2-[4-(2,3-EPOXYPROPOXY)PHENYL]ACETAMIDE Bufexamac ETHYL 3-HYDROXY-4,6-DIMETHOXY-2-OXOINDOLINE-3-CARBOXYLATE 3,4-DIMETHOXYPHENYLACETIC ACID HYDRAZIDE 4-Acetylamino-2-(diethylamino)anisole 4-Acetylamino-2-(bis(2-hydroxyethyl)amino)anisole 2',5'-DIMETHOXYACETANILIDE 4'-(Difluoromethoxy)acetanilide N-[3-[(2-Cyanoethyl)ethylamino]-4-methoxyphenyl]acetamide N-[3-[(2-Cyanoethyl)amino]-4-methoxyphenyl]acetamide 4-Acetylamino-2-(diallylamino)anisole 3'-Amino-4'-methoxyacetanilide 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide

Benzeneacetamide, 4-methoxy-

2-(4-METHOXY-PHENYL)-ACETAMIDE

4-METHOXYPHENYLACETAMIDE

PARA METHOXYL PHENYL ACETAMIDE

PARA METHOXYPHENYL ACETAMIDE

P-METHOXYPHENYLACETAMIDE

4-Methoxybenzeneacetamide

Einecs 228-745-9

2-hydroxybenzoic acid [(1R,3R,4S)-4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl] ester

6343-93-7

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts