4-METHOXYPHENYLACETAMIDE
- Product Name
- 4-METHOXYPHENYLACETAMIDE
- CAS No.
- 6343-93-7
- Chemical Name
- 4-METHOXYPHENYLACETAMIDE
- Synonyms
- Einecs 228-745-9;4-METHOXYPHENYLACETAMIDE;P-METHOXYPHENYLACETAMIDE;4-Methoxybenzeneacetamide;Benzeneacetamide, 4-methoxy-;PARA METHOXYPHENYL ACETAMIDE;PARA METHOXYL PHENYL ACETAMIDE;2-(4-METHOXY-PHENYL)-ACETAMIDE;2-hydroxybenzoic acid [(1R,3R,4S)-4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl] ester
- CBNumber
- CB6403610
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 6343-93-7.mol
4-METHOXYPHENYLACETAMIDE Property
- Melting point:
- 182-184°C
- Boiling point:
- 354.7±25.0 °C(Predicted)
- Density
- 1.123±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 16.37±0.40(Predicted)
- color
- White to Off-White
- BRN
- 2088040
- CAS DataBase Reference
- 6343-93-7(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S580813
- Product name
- 2-(4-METHOXYPHENYL)ACETAMIDE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
- Product number
- S580813
- Product name
- 2-(4-METHOXYPHENYL)ACETAMIDE
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $179
- Updated
- 2024/03/01
- Product number
- M220175
- Product name
- 4-Methoxyphenylacetamide
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2762AL
- Product name
- 4-Methoxyphenylacetamide
- Packaging
- 1g
- Price
- $81
- Updated
- 2021/12/16
- Product number
- CHM0011947
- Product name
- 4-METHOXYPHENYLACETAMIDE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1643.28
- Updated
- 2021/12/16
4-METHOXYPHENYLACETAMIDE Chemical Properties,Usage,Production
Uses
4-Methoxyphenylacetamide is a useful reagent in the preparation of novel pyrrolidone-??based derivatives as potential p53-??MDM2 inhibitors for use as potential antitumor agents.
Synthesis
104-47-2
6343-93-7
General procedure for the synthesis of 4-methoxybenzeneacetamide from p-methoxybenzeneacetonitrile: Ni NPs/HT catalyst (0.05 g) was added to a thick-walled pressure tube, followed by water (4 ml) and p-methoxybenzeneacetonitrile (1 mmol). The reaction mixture was placed in an oil bath at 120 °C and stirred vigorously. The reaction process was monitored by TLC analysis. Upon completion of the reaction, the reaction mixture was extracted with ethyl acetate and subsequently filtered to remove the catalyst. The filtrate was cooled to 0 °C to allow white crystals to precipitate. The crystalline product was collected by simple filtration and dried under vacuum at room temperature to give analytically pure 4-methoxyphenylacetamide. If the product did not precipitate, the reaction mixture was extracted with ethyl acetate followed by purification by silica gel column chromatography to finally obtain 4-methoxyphenylacetamide.
References
[1] Synthesis, 1989, # 12, p. 949 - 951
[2] RSC Advances, 2015, vol. 5, # 9, p. 6365 - 6371
[3] Zeitschrift fur Chemie, 1980, vol. 20, # 10, p. 380 - 380
[4] Catalysis Communications, 2012, vol. 29, p. 109 - 113
[5] Green Chemistry, 2014, vol. 16, # 4, p. 2136 - 2141
4-METHOXYPHENYLACETAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-METHOXYPHENYLACETAMIDE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@chemsworth.com
- Country
- India
- ProdList
- 6700
- Advantage
- 30
- Tel
- --
- Fax
- --
- otcchem@otcchem.com
- Country
- India
- ProdList
- 6202
- Advantage
- 58