Pilocarpine nitrate
- Product Name
- Pilocarpine nitrate
- CAS No.
- 148-72-1
- Chemical Name
- Pilocarpine nitrate
- Synonyms
- Nitrat;Pilocarpine nitrate for system suitability CRS;Pilagan;pilofrin;Pilocarpinnitrat;Einecs 205-723-7;Pilocarpin Nitrate;Pilocarpini nitras;PILOCARPINE NITRATE;p.v.carpineliquifilm
- CBNumber
- CB4237796
- Molecular Formula
- C11H17N3O5
- Formula Weight
- 271.27
- MOL File
- 148-72-1.mol
Pilocarpine nitrate Property
- Melting point:
- 173,5-174°C
- alpha
- D +77 to +83° (c = 10)
- refractive index
- 81 ° (C=2, H2O)
- storage temp.
- 2-8°C
- solubility
- H2O: 0.1 g/mL, clear, very faintly yellow
- form
- powder
- color
- white
- optical activity
- [α]25/D +83°, c = 10 in H2O(lit.)
- Merck
- 14,7424
- BRN
- 4171406
- CAS DataBase Reference
- 148-72-1(CAS DataBase Reference)
- EPA Substance Registry System
- Pilocarpine nitrate (148-72-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H272May intensify fire; oxidizer
H302Harmful if swallowed
H330Fatal if inhaled
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P220Keep/Store away from clothing/…/combustible materials.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- P0597
- Product name
- Pilocarpine nitrate
- Purity
- meets USP testing specifications
- Packaging
- 5g
- Price
- $439
- Updated
- 2024/03/01
- Product number
- P0597
- Product name
- Pilocarpine nitrate
- Purity
- meets USP testing specifications
- Packaging
- 25g
- Price
- $918
- Updated
- 2024/03/01
- Product number
- BP503
- Product name
- Pilocarpine nitrate
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 200MG
- Price
- $223
- Updated
- 2024/03/01
- Product number
- Y0000106
- Product name
- Pilocarpine nitrate for system suitability
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0000106
- Price
- $153
- Updated
- 2024/03/01
- Product number
- P6628
- Product name
- Pilocarpine nitrate salt
- Purity
- ≥98% (HPLC)
- Packaging
- 10g
- Price
- $244
- Updated
- 2024/03/01
Pilocarpine nitrate Chemical Properties,Usage,Production
Chemical Properties
White or almost white, crystalline powder or colourless crystals, sensitive to light.
Uses
antiglaucoma agent, miotic
Uses
Antiglaucoma drug;Cholinergic
Uses
Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.
brand name
Pilagan (Allergan).
General Description
Pilocarpine mononitrate occursas shining white crystals that are not hygroscopic butare light sensitive. It is soluble in water (1:4) and alcohol(1:75) but insoluble in chloroform and ether. Aqueoussolutions are slightly acid to litmus and may be sterilizedin the autoclave. The alkaloid is incompatible with alkalies,iodides, silver nitrate, and reagents that precipitatealkaloids.
Biochem/physiol Actions
Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.
Pilocarpine nitrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pilocarpine nitrate manufacturers
- Product
- Pilocarpine nitrate 148-72-1
- Price
- US $35.00-1.30/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28
- Product
- Pilocarpine nitrate 148-72-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-27