5-CYANOTHIAZOLE
- Product Name
- 5-CYANOTHIAZOLE
- CAS No.
- 25742-12-5
- Chemical Name
- 5-CYANOTHIAZOLE
- Synonyms
- 5-CYANOTHIAZOLE;5-Thiazolecarbonitrile;THIAZOLE-5-CARBONITRILE;1,3-thiazole-5-carbonitrile;5-Thiazolecarbonitrile (8CI, 9CI, ACI);Thiazole-5-carbonitrile , 5-Cyanothiazole
- CBNumber
- CB42448547
- Molecular Formula
- C4H2N2S
- Formula Weight
- 110.14
- MOL File
- 25742-12-5.mol
5-CYANOTHIAZOLE Property
- Melting point:
- 53 °C
- Boiling point:
- 90-93 °C(Press: 15 Torr)
- Density
- 1.33
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -0.40±0.10(Predicted)
- Appearance
- Yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H371May cause damage to organs
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309+P311IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T430253
- Product name
- Thiazole-5-carbonitrile
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- T430253
- Product name
- Thiazole-5-carbonitrile
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- P000147149
- Product name
- Thiazole-5-carbonitrile
- Purity
- 98%
- Packaging
- 250mg
- Price
- $102
- Updated
- 2021/12/16
- Product number
- P000147149
- Product name
- Thiazole-5-carbonitrile
- Purity
- 98%
- Packaging
- 1g
- Price
- $261
- Updated
- 2021/12/16
- Product number
- 7H37-1-0G
- Product name
- 5-Cyanothiazole
- Purity
- 95%
- Packaging
- 250mg
- Price
- $376
- Updated
- 2021/12/16
5-CYANOTHIAZOLE Chemical Properties,Usage,Production
Synthesis
116045-57-9
25742-12-5
1,3-Thiazole-5-carboxaldehyde oxime (2.5 g, 19.5 mmol, 1 eq.) was used as a starting material, which was dissolved in 12 mL of dioxane, followed by the addition of triethylamine (TEA, 6.8 mL, 2.5 eq.). The reaction mixture was cooled to 0 °C and trifluoroacetic anhydride (3.0 mL, 1.1 eq.) was added slowly and dropwise. The reaction solution was stirred overnight at room temperature and then trifluoroacetic anhydride (1.1 eq.) was added again to ensure complete reaction. Stirring was continued overnight at room temperature followed by solvent evaporation. The residue was dissolved in dichloromethane (DCM) and washed five times with water. The organic layer was dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give 1.25 g of 1,3-thiazole-5-carbonitrile in 58% yield.
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 1, p. 68 - 83
[2] Patent: WO2013/60744, 2013, A2. Location in patent: Page/Page column 11; 12
5-CYANOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-CYANOTHIAZOLE manufacturers
- Product
- 5-Cyanothiazole 25742-12-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27