ChemicalBook > CAS DataBase List > 5-CYANOTHIAZOLE

5-CYANOTHIAZOLE

Product Name
5-CYANOTHIAZOLE
CAS No.
25742-12-5
Chemical Name
5-CYANOTHIAZOLE
Synonyms
5-CYANOTHIAZOLE;Thiazol-5-carbonitrile;5-Thiazolecarbonitrile;THIAZOLE-5-CARBONITRILE;1,3-thiazole-5-carbonitrile;5-Thiazolecarbonitrile (8CI, 9CI, ACI);Thiazole-5-carbonitrile , 5-Cyanothiazole
CBNumber
CB42448547
Molecular Formula
C4H2N2S
Formula Weight
110.14
MOL File
25742-12-5.mol
More
Less

5-CYANOTHIAZOLE Property

Melting point:
53 °C
Boiling point:
90-93 °C(Press: 15 Torr)
Density 
1.33
storage temp. 
Sealed in dry,Room Temperature
pka
-0.40±0.10(Predicted)
Appearance
Yellow to brown Solid
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2934100090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H371May cause damage to organs

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309+P311IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
T430253
Product name
Thiazole-5-carbonitrile
Packaging
50mg
Price
$65
Updated
2021/12/16
TRC
Product number
T430253
Product name
Thiazole-5-carbonitrile
Packaging
250mg
Price
$240
Updated
2021/12/16
SynQuest Laboratories
Product number
7H37-1-0G
Product name
5-Cyanothiazole
Purity
95%
Packaging
1g
Price
$952
Updated
2021/12/16
Ark Pharm
Product number
P000147149
Product name
Thiazole-5-carbonitrile
Purity
98%
Packaging
5g
Price
$1044
Updated
2021/12/16
Matrix Scientific
Product number
072673
Product name
5-Cyanothiazole
Purity
95+%
Packaging
1g
Price
$1357
Updated
2021/12/16
More
Less

5-CYANOTHIAZOLE Chemical Properties,Usage,Production

Synthesis

116045-57-9

25742-12-5

1,3-Thiazole-5-carboxaldehyde oxime (2.5 g, 19.5 mmol, 1 eq.) was used as a starting material, which was dissolved in 12 mL of dioxane, followed by the addition of triethylamine (TEA, 6.8 mL, 2.5 eq.). The reaction mixture was cooled to 0 °C and trifluoroacetic anhydride (3.0 mL, 1.1 eq.) was added slowly and dropwise. The reaction solution was stirred overnight at room temperature and then trifluoroacetic anhydride (1.1 eq.) was added again to ensure complete reaction. Stirring was continued overnight at room temperature followed by solvent evaporation. The residue was dissolved in dichloromethane (DCM) and washed five times with water. The organic layer was dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give 1.25 g of 1,3-thiazole-5-carbonitrile in 58% yield.

References

[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 1, p. 68 - 83
[2] Patent: WO2013/60744, 2013, A2. Location in patent: Page/Page column 11; 12

5-CYANOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-CYANOTHIAZOLE Suppliers

China 46 Germany 1 India 1 United States 9 Global 57
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.
Tel
21-54820552 18964669552
Fax
086-21-64964478
Email
188738128@qq.com
Country
China
ProdList
310
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Chiba Pharmaceutical Science and technology Co, Ltd.
Tel
0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
Country
China
ProdList
3991
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ShangHai Wisacheam Pharmaceutical Co., Ltd.
Tel
13817485796
Fax
QQ:895624079
Email
tim@wisacheampharm.com
Country
China
ProdList
3593
Advantage
58
Yancheng Schiemann Biological Technology Co.,Ltd
Tel
515-88280676 18921872653
Email
sales@ximanbio.com
Country
China
ProdList
1524
Advantage
56
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Huaian Hyperion pharmaceutical R&D Co.,Ltd.
Tel
18114966287
Fax
-
Email
sales@hyperionpharm.com
Country
China
ProdList
449
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15083
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9721
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Wuxi jinluoli Pharmaceutical Technology Co., Ltd.
Tel
18021193238
Fax
QQ：534936027
Email
534936027@qq.com
Country
China
ProdList
363
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10267
Advantage
58
Xinyi Kaiwu Chemical Technology Co., Ltd.
Tel
0516-0516-88997009 18651776937
Email
4164357@qq.com
Country
China
ProdList
3204
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10237
Advantage
58
CD Chemical Group Limited
Tel
+8615986615575
Fax
0086-13651442114
Email
info@codchem.com
Country
China
ProdList
20342
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Zhengzhou convergence chemical co., LTD
Tel
0371-0371-55153829 18003835034
Email
2853979819@qq.com
Country
China
ProdList
9998
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Beijing InnoChem Science & Technology Co., Ltd.
Tel
15652467323
Email
sales@inno-chem.com.cn
Country
China
ProdList
8293
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Xi'an Meike Biotechnology Co., Ltd
Tel
029-18710438009 18710438009
Email
2671807997@qq.com
Country
China
ProdList
1027
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29995
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
syeu@accelachem.com
Country
China
ProdList
11015
Advantage
58
Shanghai Shiyi Reagent Co., Ltd
Tel
02118516225986 18516225986
Email
997491952@qq.com
Country
China
ProdList
108
Advantage
58
Tianjin Find Technology Development Co.,Ltd
Tel
15620920485; 15620920485
Email
823251269@qq.com
Country
China
ProdList
1266
Advantage
58
Woerjiming (Beijing) Technology Development Institute
Tel
18610294897
Email
414752910@qq.com
Country
China
ProdList
1370
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
33024
Advantage
60
DAYANG CHEM (HANGZHOU) CO.,LTD
Tel
+86-88938639 +86-17705817739
Email
info@dycnchem.com
Country
China
ProdList
53899
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39002
Advantage
58
HANGZHOU LEAP CHEM CO., LTD.
Tel
+86-571-87711850
Email
market18@leapchem.com
Country
China
ProdList
43339
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
ShangHai molecular Chemical Co., Ltd
Tel
--
Fax
--
Email
sales@molecular-chem.com
Country
China
ProdList
29
Advantage
30
More
Less

View Lastest Price from 5-CYANOTHIAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Cyanothiazole 25742-12-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

25742-12-5, 5-CYANOTHIAZOLERelated Search:

2-CHLOROTHIAZOLE-5-CARBONITRILE 2-AMINOTHIAZOLE-5-CARBONITRILE 5-CYANOTHIAZOLE 4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBONITRILE 2-[2-(DIMETHYLAMINO)VINYL]-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBONITRILE 2-(AMINOMETHYL)THIAZOLE-5-CARBONITRILE HYDROCHLORIDE 2-AMINO-4-(TERT-BUTYL)-1,3-THIAZOLE-5-CARBONITRILE 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE 4-chloro-2-[(2-pyridinylmethyl)amino]-1,3-thiazole-5-carbonitrile 2-(benzylamino)-4-chloro-1,3-thiazole-5-carbonitrile 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBONITRILE 4-chloro-2-[(2-thienylmethyl)amino]-1,3-thiazole-5-carbonitrile 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBONITRILE 4-chloro-2-[(2-hydroxypropyl)amino]-1,3-thiazole-5-carbonitrile 2-[2-(4-CHLOROANILINO)VINYL]-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBONITRILE 2-(2-([(4-CHLOROBENZYL)OXY]IMINO)ETHYL)-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBONITRILE N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-4-methylbenzenecarboxamide 2-[2-(4-METHOXYANILINO)VINYL]-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBONITRILE

  • 5-CYANOTHIAZOLE
  • THIAZOLE-5-CARBONITRILE
  • 1,3-thiazole-5-carbonitrile
  • 5-Thiazolecarbonitrile
  • 5-Thiazolecarbonitrile (8CI, 9CI, ACI)
  • Thiazole-5-carbonitrile , 5-Cyanothiazole
  • Thiazol-5-carbonitrile
  • 25742-12-5