6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
- Product Name
- 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
- CAS No.
- 99368-68-0
- Chemical Name
- 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
- Synonyms
- 6-Chloro-5-(trifluoromethyl);6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE;6-chloro-5-(trifluoromethyl)-3-Pyridinamine;6-Chloro-5-trifluoroMethyl-pyridin-3-ylaMine;3-Amino-6-chloro-5-(trifluoromethyl)pyridine;3-Pyridinamine, 6-chloro-5-(trifluoromethyl)-;6-chloro-5-(trifluoromethyl)pyridin-3-amine - [C27002]
- CBNumber
- CB42455918
- Molecular Formula
- C6H4ClF3N2
- Formula Weight
- 196.56
- MOL File
- 99368-68-0.mol
6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE Property
- Boiling point:
- 292℃
- Density
- 1.507
- Flash point:
- 130℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- Light yellow to light brown Solid
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- C351485
- Product name
- 6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- C351485
- Product name
- 6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- PC201388
- Product name
- 6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $68
- Updated
- 2021/12/16
- Product number
- 3H30-7-1D
- Product name
- 6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- Purity
- 95.0%
- Packaging
- 100mg
- Price
- $109
- Updated
- 2021/12/16
- Product number
- 119596
- Product name
- 6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $224
- Updated
- 2021/12/16
6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE Chemical Properties,Usage,Production
Synthesis
99368-67-9
99368-68-0
A solution of 5% Pt/C (1.58 mmol, 0.31 g) in ethyl acetate (50 mL) was added to 2-chloro-5-nitro-3-(trifluoromethyl)pyridine (5.25 mmol, 1.19 g) mixed with ZnBr2 (1.05 mmol, 0.200 g) and the reaction was stirred for 20 hrs under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the solid was washed with warm ethanol. The solvent was evaporated to afford the target product 6-chloro-5-(trifluoromethyl)pyridin-3-amine (0.95 g, 92% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 5.59 (bs, 1H), 7.37 (s, 1H), 7.92 (s, 1H).
References
[1] Patent: WO2018/20474, 2018, A1. Location in patent: Page/Page column 309-310
[2] Patent: WO2009/21696, 2009, A1. Location in patent: Page/Page column 38; 69-70
[3] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 39
[4] Patent: US2014/275111, 2014, A1. Location in patent: Paragraph 0280; 0281
[5] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 60
6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE manufacturers
- Product
- 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE 99368-68-0
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-08-13