SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE

Product Name: SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE
CAS No.: 356072-46-3
Chemical Name: SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE
Synonyms: Spiro[indoline-3,4'-piperidin]-2-one, HCl;Spiro[indoline-3,4'-piperidin]-2-one hydrochloride;Spiro[indoline-3,4'-piperidin]-2-one hydrochloride;spiro[1H-indole-3,4'-piperidine]-2-one,hydrochloride;Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, hydrochloride;1,2-Dihydrospiro[indole-3,4'-piperidine]-2-one hydrochloride;Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, hydrochloride (1:1);1,2-Dihydro-2-oxo-spiro[3H-indole-3,4'-piperidine] hydrochloride;Spiro[3H-indole-3,4′-piperidin]-2(1H)-one Hydrochloride, CAS 356072-46-3
CBNumber: CB42468846
Molecular Formula: C12H15ClN2O
Formula Weight: 238.7133
MOL File: 356072-46-3.mol

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SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: White to off-white Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: S682995
Product name: Spiro[3H-indole-3,4''-piperidin]-2(1H)-oneHydrochloride
Packaging: 5g
Price: $1260
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 53046
Product name: Spiro[3H-indole-3,4??-piperidin]-2(1H)-oneHCl
Packaging: 500mg
Price: $650
Updated: 2021/12/16

AK Scientific

Product number: 4445AB
Product name: Spiro[indoline-3,4'-piperidin]-2-onehydrochloride
Packaging: 1g
Price: $779
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0158297
Product name: SPIRO(INDOLINE-3,4'-PIPERIDIN)-2-ONE HYDROCHLORIDE
Purity: 95.00%
Packaging: 5G
Price: $3811.5
Updated: 2021/12/16

J&W Pharmlab

Product number: 48R0753S
Product name: 1,2-Dihydro-2-oxo-spiro[3H-indole-3,4''-piperidine]hydrochloride
Purity: 96%
Packaging: 1g
Price: $998
Updated: 2021/12/16

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SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Spiro[3H-indole-3,4''-piperidin]-2(1H)-one Hydrochloride, can be used as high-affinity, selective σ ligands.

Synthesis

356072-45-2

356072-46-3

1'-(Benzyloxycarbonyl)spiro[3H-indole-3,4'-piperidin]-2(1H)-one (74.6 mg) was used as a raw material and dissolved in methanol (1.5 mL). 10% palladium/carbon catalyst (14 mg) was added and the reaction was stirred at room temperature under hydrogen atmosphere for 4 hours. Upon completion of the reaction, the insoluble material was removed by filtration. To the filtrate, 1N aqueous hydrochloric acid (0.33 mL) was added, followed by evaporation of the solvent under reduced pressure to afford spiro[indoline-3,4-piperidin]-2-one hydrochloride (51.7 mg) in 98% yield. The product was characterized by 1H-NMR (D2O): δ 2.11 (4H, m), 3.48 (2H, m), 3.72 (2H, m), 7.07 (1H, d, J = 8 Hz), 7.18 (1H, t, J = 8 Hz), 7.35 (1H, t, J = 8 Hz), 7.45 (1H, d, J = 8 Hz). Mass spectrometry (TSP) analysis showed: m/z 203 (MH+).

References

[1] Patent: US2003/171370, 2003, A1

SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDE Suppliers

China 32 India 2 United States 4 Global 38

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356072-46-3, SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE HYDROCHLORIDERelated Search:

SPIRO[INDOLINE-3,4'-PIPERIDIN]-2-ONE SPIRO[2.5]OCTAN-6-ONE ISOINDOLIN-1-ONE spiro[indole-3,3-pyrrolidin]-2(1H)-one hydrochloride

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, hydrochloride (1:1)

Spiro[3H-indole-3,4'-piperidin]-2(1H)-one, hydrochloride

1,2-Dihydro-2-oxo-spiro[3H-indole-3,4'-piperidine] hydrochloride

1,2-Dihydrospiro[indole-3,4'-piperidine]-2-one hydrochloride

Spiro[indoline-3,4'-piperidin]-2-one, HCl

spiro[1H-indole-3,4'-piperidine]-2-one,hydrochloride

Spiro[indoline-3,4'-piperidin]-2-one hydrochloride

Spiro[3H-indole-3,4′-piperidin]-2(1H)-one Hydrochloride, CAS 356072-46-3

Spiro[indoline-3,4'-piperidin]-2-one hydrochloride

356072-46-3