DGAT-1 inhibitor

Product Name: DGAT-1 inhibitor
CAS No.: 959122-11-3
Chemical Name: DGAT-1 inhibitor
Synonyms: CS-121;A922500;DGAT-1 inhibitor;DGAT-1 Inhibitor 4a;DGAT-1 Inhibitor, A 922500;DGAT-1 inhibitor USP/EP/BP;A922500(DGAT-1 Inhibitor 4a);DGAT-1 Inhibitor A922500 A-922500;DGAT-1 INHIBITOR 4A; A-922500; A922500;Diacyl glycerolacyltransferase 1 inhibitor
CBNumber: CB42470944
Molecular Formula: C26H24N2O4
Formula Weight: 428.48
MOL File: 959122-11-3.mol

More

Less

DGAT-1 inhibitor Property

Density: 1.323
storage temp.: -20°C
solubility: ≥21.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form: Light yellow solid

More

Less

Safety

Hazard Codes: T,N
Risk Statements: 25-36-50
Safety Statements: 26-45-61
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A1737
Product name: A922500
Packaging: 1MG
Price: $57.5
Updated: 2023/06/20

Sigma-Aldrich

Product number: A1737
Product name: A922500
Packaging: 5MG
Price: $242
Updated: 2023/06/20

Sigma-Aldrich

Product number: A1737
Product name: A922500
Packaging: 10MG
Price: $413
Updated: 2023/06/20

Sigma-Aldrich

Product number: 252801
Product name: DGAT-1 Inhibitor, A 922500
Packaging: 5mg
Price: $298
Updated: 2022/05/15

Cayman Chemical

Product number: 10012708
Product name: A-922500
Purity: ≥95%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

More

Less

DGAT-1 inhibitor Chemical Properties,Usage,Production

Uses

A922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages.

Definition

ChEBI: A 922500 is an aromatic ketone.

Biological Activity

Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC 50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food intake, and decreases liver and plasma triglyceride levels in vivo . Orally active.

Biochem/physiol Actions

The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease.

DGAT-1 inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DGAT-1 inhibitor Suppliers

China 103 United Kingdom 2 United States 21 Global 126

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

ApexBio Technology LLC

Tel: +1-832-696-8203
Fax: +1-832-641-3177
Email: info@apexbt.com
Country: United States
ProdList: 477
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Creative Enzymes

Tel: --
Fax: --
Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Axon Medchem LLC

Tel: --
Fax: --
Email: info@axonmedchem.com
Country: United States
ProdList: 763
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

More

Less

View Lastest Price from DGAT-1 inhibitor manufacturers

Career Henan Chemical Co

Product: (1R,2R)-2-[[4'-[[(Phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid 959122-11-3
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

959122-11-3, DGAT-1 inhibitorRelated Search:

Urease inhibitor NS-398 (1R,2R)-1-(tert-butoxycarbonylamino)-2-(difluoromethyl)cyclopropanecarboxylic acid Selumetinib PF-562271 Quizartinib (AC220) GSK256066 SGX-523 Tofacitinib

(1R,2R)-2-[[4'-[[(Phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid

DGAT-1 inhibitor

Diacyl glycerolacyltransferase 1 inhibitor

A922500

A922500(DGAT-1 Inhibitor 4a)

enylureido)biphenyl(1R,2R)-2-(4'-(3-phcarbonyl)cyclopentanecarboxylic acid

DGAT-1 Inhibitor 4a

(1R,2R)-2-(4'-(3-phenylureido)biphenylcarbonyl)cyclopentanecarboxylic acid

Cyclopentanecarboxylic acid, 2-[[4'-[[(phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]-, (1R,2R)-

(1R,2R)-2-(4,-(3-phenylureido)-[1,1,-biphenyl]-4-carbonyl)cyclopentanecarboxylic acid

DGAT-1 Inhibitor, A 922500

CS-121

DGAT-1 Inhibitor, A 922500 - CAS 959122-11-3 - Calbiochem

DGAT-1 INHIBITOR 4A; A-922500; A922500

DGAT-1 inhibitor USP/EP/BP

DGAT-1 Inhibitor A922500 A-922500

(1R,2R)-2-(4'-(3-Phenylureido)-[1,1'-biphenyl]-4-carbonyl)cyclopentanecarboxylic acid

959122-11-3

Inhibitor

Inhibitors

APIs