ChemicalBook > CAS DataBase List > 1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product Name
1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS No.
1002334-12-4
Chemical Name
1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms
1-Phenylpyrazole-4-boronic acid, pinacol ester;1-Phenyl-1H-pyrazole-4-boronic acid picol ester;1-phenyl-1H-pyrazole-4-boronic acid pinacol ester;(1-PHENYL-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER;1-phenyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-...;1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxanborane-2-YL)-1H-pyrazole;1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1H-Pyrazole, 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber
CB42475893
Molecular Formula
C15H19BN2O2
Formula Weight
270.13
MOL File
1002334-12-4.mol
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1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Property

Boiling point:
389.8±15.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pka
-0.58±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C15H19BN2O2/c1-14(2)15(3,4)20-16(19-14)12-10-17-18(11-12)13-8-6-5-7-9-13/h5-11H,1-4H3
InChIKey
XPAJFLOIPDXRRD-UHFFFAOYSA-N
SMILES
N1(C2=CC=CC=C2)C=C(B2OC(C)(C)C(C)(C)O2)C=N1
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Safety

HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
P399698
Product name
1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Packaging
25g
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-W000782
Product name
1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Purity
≥97.0%
Packaging
1g
Price
$119
Updated
2021/12/16
Synthonix
Product number
P15917
Product name
1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Purity
97%
Packaging
1g
Price
$160
Updated
2021/12/16
SynQuest Laboratories
Product number
8H60-1-FZ
Product name
1-Phenylpyrazole-4-boronic acid, pinacol ester
Purity
97%
Packaging
1g
Price
$184
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BOR0003296
Product name
1-PHENYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE
Purity
95.00%
Packaging
1G
Price
$413.7
Updated
2021/12/16
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1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Chemical Properties,Usage,Production

Synthesis

15115-52-3

73183-34-3

1002334-12-4

The general procedure for the synthesis of 1-phenyl-1H-pyrazole-4-boronic acid pinacol ester from 4-bromo-1-phenyl-1H-pyrazole and biboronic acid pinacol ester was as follows: to a solution of 4-bromo-1-phenyl-1H-pyrazole (0.5 g, 2.3 mmol) in DMSO (50 mL) was added sequentially at room temperature KOAc (0.66 g, 6.8 mmol), bis( pinacolato) diboron (0.63 g, 2.5 mmol) and PdCl2(dppf) (0.076 g, 0.11 mmol). The reaction mixture was stirred at 80 °C overnight. After completion of the reaction, the mixture was diluted with ethyl acetate, washed with saturated brine, dried over anhydrous sodium sulfate, concentrated and purified by column chromatography (eluent ratio: ethyl acetate:petroleum ether = 1:12) to afford 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (0.3 g, 50% yield) as a light yellow solid.

References

[1] Patent: WO2009/155527, 2009, A2. Location in patent: Page/Page column 134

1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Suppliers

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View Lastest Price from 1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole manufacturers

Career Henan Chemical Co
Product
1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1002334-12-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,50kg
Release date
2020-01-16

1002334-12-4, 1-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleRelated Search:

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