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nimotuzumab

Product Name
nimotuzumab
CAS No.
828933-51-3
Chemical Name
nimotuzumab
Synonyms
nimotuzumab;Research Grade Nimotuzumab(DHB86914)
CBNumber
CB42498825
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BN165591
Product name
Nimotuzumab
Packaging
1mg
Price
$600
Updated
2021/12/16
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nimotuzumab Chemical Properties,Usage,Production

Description

Overexpression of epidermal growth factor receptor (EGFR), a transmembrane receptor tyrosine kinase, is prevalent in malignant tumors of epithelial origin and is especially common in breast, head and neck, colon, and lung cancer. With EGFR overexpression, prognosis is poor due to associated tumor invasion, metastasis, enhanced angiogenesis, and resistance to chemotherapy; thus, modulation of EGFR-mediated signaling is an attractive target for intervention. Small-molecule kinase inhibitors (gefitinib and erlotinib) and a monoclonal antibody (cetuximab) specific for EGFR are in clinical evaluation, but treatment cessation due to development of severe acne-like rash is common with these EGFR antagonists. Notably, nimotuzumab, a humanized form of the murine IgG2a monoclonal antibody that has been launched in India for treatment of head and neck cancers overexpressing EGFR, demonstrates clinical efficacy devoid of the rash toxicity. .

Originator

Center for Molecular Immunology (Cuba)

brand name

BioMab EFGR, Theraloc

nimotuzumab Preparation Products And Raw materials

Raw materials

Preparation Products

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nimotuzumab Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58