abciximab

Product Name: abciximab
CAS No.: 143653-53-6
Chemical Name: abciximab
Synonyms: Reopro;Rheopro;CentoRx;c7E3 Fab;Abcixifiban;Unii-X85G7936gv;Research Grade Abciximab(DHC33301);Immunoglobulin G1, (human-mouse monoclonal c7E3 clone p7E3VHhCgamma1 Fab fragment anti-human glycoprotein IIb/IIIa receptor), disulfide with human-mouse monoclonal c7E3 clone p7E3VkappahCkappa light chain
CBNumber: CB51319184
Formula Weight: 0
MOL File: Mol file

More

Less

abciximab Property

storage temp.: Store at -80°C

More

Less

Safety

Hazardous Substances Data: 143653-53-6(Hazardous Substances Data)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: ATB0010203
Product name: ABCIXIMAB
Purity: 98.00%
Packaging: 5MG
Price: $498
Updated: 2021/12/16

More

Less

abciximab Chemical Properties,Usage,Production

Uses

Monoclonal antibody (antithrombotic).

brand name

ReoPro (Lilly).

Clinical Use

Antiplatelet agent:
Prevention of ischaemic cardiac complications in patients undergoing percutaneous coronary intervention
Short-term prevention of myocardial infarction in patients with unstable angina not responding to treatment or awaiting percutaneous coronary intervention.

Enzyme inhibitor

This antithrombotic (MW = 47455 g/mol; CAS 143653-53-6; also known as Reopro?) consists of an immunoglobulin G1 Fab fragment from a chimeric human-murine monoclonal antibody directed against the human platelet glycoprotein IIb/IIIa receptor. Abciximab also facilitates the dispersal of newly formed platelet aggregates in vitro, by partially displacing fibrinogen from activated GPIIb/IIIareceptors. In vivo, abciximab may destabilize coronary thrombi by preventing aggregate formation and dispersing mural thrombi. Target(s): coagulation factor Xa, in presence of heparin; glycoprotein IIb/IIIa receptor.

Drug interactions

Potentially hazardous interactions with other drugs
Heparin, anticoagulants, antiplatelets and thrombolytics: increased risk of bleeding.

Metabolism

Following IV administration, abciximab rapidly binds to the platelet GPIIb/IIIa receptors, and remains in the circulation for 15 days or more in a platelet-bound state. Metabolism is via proteolytic cleavage

abciximab Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

abciximab Suppliers

China 15 United States 2 Global 17

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Wuhan Chemstan Biotechnology Co., Ltd.

Tel: 027-65317797 15926423062
Fax: QQ：422450190
Email: 422450190@qq.com
Country: China
ProdList: 10055
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7955
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7977
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 17691182729 18161915376
Email: 1046@dideu.com
Country: China
ProdList: 10010
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9892
Advantage: 58

AntibodySystem

Tel: 027-65279366 18162686757
Email: biolab-reagents@atagenix.com
Country: China
ProdList: 9800
Advantage: 58

143653-53-6, abciximabRelated Search:

Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Tosylmethyl isocyanide SALCOMINE PHENYLSELENOL TERT-BUTYL ISOCYANIDE Aluminum acetylacetonate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE Ethyl isocyanoacetate Cupric acetylacetonate METHYL ISOCYANOACETATE Benzyl isocyanide Tris(2,4-pentanedionato)chroMiuM(III) N-BUTYLISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)

Reopro

Unii-X85G7936gv

CentoRx

Immunoglobulin G1, (human-mouse monoclonal c7E3 clone p7E3VHhCgamma1 Fab fragment anti-human glycoprotein IIb/IIIa receptor), disulfide with human-mouse monoclonal c7E3 clone p7E3VkappahCkappa light chain

Rheopro

Research Grade Abciximab(DHC33301)

Abcixifiban

c7E3 Fab

143653-53-6