ChemicalBook > CAS DataBase List > (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

Product Name
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
CAS No.
106083-71-0
Chemical Name
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Synonyms
GW 353162;GW-353162A;BW-306U;Bupropion Morpholinol IMpurity;SS-hydroxybupropion hydrochloride;Bupropion Morpholinol (2S,3S)-Isomer;(2S,3S)-Hydroxybupropion hydrochloride;Bupropion Morpholinol IMpurity (HCl Salt);(2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC);(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
CBNumber
CB42502638
Molecular Formula
C13H19Cl2NO2
Formula Weight
292.2
MOL File
106083-71-0.mol
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(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Property

storage temp. 
-20°C
solubility 
DMSO: ≥12mg/mL
form 
powder
color 
white to tan
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3167
Product name
(2S,3S)-Hydroxybupropion hydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$143
Updated
2024/03/01
Sigma-Aldrich
Product number
H3167
Product name
(2S,3S)-Hydroxybupropion hydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$592
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0004715
Product name
GW-353162A
Purity
95.00%
Packaging
25MG
Price
$1029.63
Updated
2021/12/16
ChemScene
Product number
CS-3815
Product name
Radafaxine(hydrochloride)
Purity
99.88%
Packaging
10mg
Price
$192
Updated
2021/12/16
ChemScene
Product number
CS-3815
Product name
Radafaxine(hydrochloride)
Purity
99.88%
Packaging
5mg
Price
$102
Updated
2021/12/16
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(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Chemical Properties,Usage,Production

Uses

Antidepressant; antianxiety.

General Description

(2S,3S)-hydroxybupropion is a major metabolite of bupropion.

Biochem/physiol Actions

(2S,3S)-hydroxybupropion is a dopamine transporter (DAT) and norepinephrine transporter (NET) transporters inhibitor and nicotinic acetylcholine receptor (nAChR) family modulator. Hydroxybupropions were reported to contribute to antidepressant and perhaps smoking cessation activities. Both (2S,3S) and (2R,3R) metabolites reverse affective and somatic withdrawal signs in nicotine-dependent mice, but (2S,3S)-hydroxybupropion is more potent. (2S,3S)-hydroxybupropion significantly decreases the development of nicotine reward in mice.

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Suppliers

China 37 India 1 United States 8 Global 46
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
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4662
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
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InvivoChem
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+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
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Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14336
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BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
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106083-71-0, (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-olRelated Search:

Bupropion 2-(TERT-BUTYLAMINO)PROPIOPHENONE HYDROCHLORIDE 2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride 1-(3-Chlorophenyl)-2-hydroxy-1-propanone Bupropion Hydrochloride Bupropion Hydrochloride Related Compound B (15 mg) (2-(tert-butylamino)-3'-bromopropiophenone hydrochloride) 2-(tert-ButylaMino)-3',4'-chloropropiophenone hydrochloride Bupropion Hydrochloride Related Compound A (15 mg) (2-(tert-butylamino)-4'-chloropropiophenone hydrochloride) 2-(tert-ButylaMino)-2'-chloropropiophenone Hydrochloride (R,R)-Hydroxy Bupropion

  • (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride
  • (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride
  • (2S,3S)-Hydroxybupropion hydrochloride
  • GW 353162
  • SS-hydroxybupropion hydrochloride
  • (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
  • Bupropion Morpholinol (2S,3S)-Isomer
  • Bupropion Morpholinol IMpurity
  • Bupropion Morpholinol IMpurity (HCl Salt)
  • GW-353162A;BW-306U
  • (2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC)
  • (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
  • 106083-71-0