rac Lafutidine
- Product Name
- rac Lafutidine
- CAS No.
- 206449-93-6
- Chemical Name
- rac Lafutidine
- Synonyms
- (Z)-FRG-8813;(Z)-Lafutidine;rac Lafutidine
- CBNumber
- CB42512282
- Molecular Formula
- C22H29N3O4S
- Formula Weight
- 431.55
- MOL File
- 206449-93-6.mol
rac Lafutidine Property
- Melting point:
- 94-99°C
- Boiling point:
- 704.2±60.0 °C(Predicted)
- Density
- 1.252
- storage temp.
- Amber Vial, -20°C Freezer
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 13.13±0.46(Predicted)
- color
- White to Pale Yellow
- Stability:
- Light Sensitive
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- L168500
- Product name
- racLafutidine
- Packaging
- 25mg
- Price
- $295
- Updated
- 2021/12/16
rac Lafutidine Chemical Properties,Usage,Production
Chemical Properties
rac Lafutidine is Off-White Solid
Uses
rac Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.
Uses
Second generation histamine H2-receptor antagonist. Antiulcerative.
Definition
ChEBI: Lafutidine is an organic molecular entity.
in vivo
(Z)-Lafutidine (Compound 16) stimulates mucin biosynthesis in rat gastric mucosa and this effect not directly due to histamine H2 receptor antagonism[1].
| Animal Model: | Eight- to nine-week-old male C57BL/6 mice weighing 20-24g[1] |
| Dosage: | 3-30 mg/kg |
| Administration: | P.o; twice for 6 days (5-FU: 50 mg/kg; i.p.;once daily) |
| Result: | Reduced the severity of diarrhea during 5-FU treatment,in a mostly dose-dependent manner, and a significant effect was observed at a dose of 30 mg/kg. |
rac Lafutidine Preparation Products And Raw materials
Raw materials
Preparation Products
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