GLYX 13

Product Name: GLYX 13
CAS No.: 117928-94-6
Chemical Name: GLYX 13
Synonyms: GLYX 13;GIYX-13;CS-1640;Rapastinel;TPPT-amide;GLYX 13 TFA;UNII-6A1X56B95E;NRX-1074 GLYX-13;GLYX13(Rapastinel);Rapastinel(GLYX-13)
CBNumber: CB42518800
Molecular Formula: C18H31N5O6
Formula Weight: 413.47
MOL File: 117928-94-6.mol

More

Less

GLYX 13 Property

Boiling point:: 844.2±65.0 °C(Predicted)
Density: 1.370±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMF: 25 mg/ml; DMSO: 15 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form: powder
pka: 12.26±0.45(Predicted)
color: white to tan
Water Solubility: Soluble to 2 mg/ml in water

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0109
Product name: GLYX-13 trifluoroacetate
Purity: ≥98% (HPLC)
Packaging: 1mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 21385
Product name: GLYX 13
Purity: ≥98%
Packaging: 1mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 21385
Product name: GLYX 13
Purity: ≥98%
Packaging: 5mg
Price: $426
Updated: 2024/03/01

Tocris

Product number: 3406
Product name: GLYX13
Packaging: 1
Price: $150
Updated: 2021/12/16

TRC

Product number: G650020
Product name: GLYX-13
Packaging: 1mg
Price: $60
Updated: 2021/12/16

More

Less

GLYX 13 Chemical Properties,Usage,Production

Uses

Rapastinel is a novel antidepressant drug approved as an adjunctive therapy for the treatment of treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-orally active) amidated tetrapeptide (Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax ≈ 25%).The drug is a rapid-acting and long-lasting antidepressant as well as robust cognitive enhancer by virtue of its ability to both inhibit and enhance NMDA receptor-mediated signal transduction.

Uses

GLYX-13 is a long lasting and rapid acting antidepressant. Investigational drug for the treatment of depressive disoder.

Uses

GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor.

Biochem/physiol Actions

GLYX-13 is a glycine-site functional partial agonist (GFPA) selective modulator of the NMDA receptor (NMDAR). It is a brain penetrable tetrapeptide which acts as a positive allosteric modulator of the NMDA receptor, acting via the glycine site. GLYX-13 has been found to be a cognitive enhancer in learning models and is currently in clinical trials as an antidepressant.

storage

Store at -20°C

GLYX 13 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GLYX 13 Suppliers

China 116 India 1 United Kingdom 1 United States 14 Global 132

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1925
Advantage: 55

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5873
Advantage: 58

More

Less

View Lastest Price from GLYX 13 manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: GLYX-13 117928-94-6
Price: US $30.00/box
Min. Order: 1box
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-03-21

Baoji Guokang Bio-Technology Co., Ltd.

Product: Rapastinel 117928-94-6
Price: US $240.00/g
Min. Order: 1g/Bag
Purity: 98%
Supply Ability: 10KG
Release date: 2021-06-04

Baoji Guokang Bio-Technology Co., Ltd.

Product: GLYX 13 117928-94-6
Price: US $238.00/g
Min. Order: 1g
Purity: 95%
Supply Ability: 100KG
Release date: 2021-06-05

117928-94-6, GLYX 13Related Search:

Linezolid Teriparatide acetate RESIQUIMOD

L-ThreoninaMide, L-threonyl-L-prolyl-L-prolyl-

GLYX-13 trifluoroacetate

L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate

GLYX 13

Thr-Pro-Pro-Thr-NH2 trifluoroacetate

TPPT-amide trifluoroacetate

Rapastinel

GIYX-13

L-Threonyl-L-prolyl-L-prolyl-L-threoninamide

GLYX-13 trifluoroacetate,Rapastinel

GLYX13(Rapastinel)

(S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide

CS-1640

GLYX-13;GLYX 13;GLYX13

Rapastinel(GLYX-13)

UNII-6A1X56B95E

Rapastinel,GLYX-13,Thr-Pro-Pro-Thr-NH2, >99%

GLYX-13;GLYX13;GLYX 13;THR-PRO-PRO-THR-NH2

Thr-Pro-Pro-Thr-NH2

TPPT-amide

(2s)-1-[(2s)-1-[(2s,3r)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-n-[(2s,3r)-1-amino-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide

(S)-1-(L-threonyl-L-prolyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)pyrrolidine-2-carboxamide

NRX-1074 GLYX-13

Rapastinel (GLYX-13) acetate

GLYX 13 TFA

117928-94-6

C18H31N5O6