GLYX 13

Product Name: GLYX 13
CAS No.: 117928-94-6
Chemical Name: GLYX 13
Synonyms: GLYX 13;GIYX-13;CS-1640;Rapastinel;TPPT-amide;GLYX 13 TFA;UNII-6A1X56B95E;NRX-1074 GLYX-13;GLYX13(Rapastinel);Rapastinel(GLYX-13)
CBNumber: CB42518800
Molecular Formula: C18H31N5O6
Formula Weight: 413.47
MOL File: 117928-94-6.mol

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GLYX 13 Property

Boiling point:: 844.2±65.0 °C(Predicted)
Density: 1.370±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMF: 25 mg/ml; DMSO: 15 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form: powder
pka: 12.26±0.45(Predicted)
color: white to tan
Water Solubility: Soluble to 2 mg/ml in water

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0109
Product name: GLYX-13 trifluoroacetate
Purity: ≥98% (HPLC)
Packaging: 1mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 21385
Product name: GLYX 13
Purity: ≥98%
Packaging: 1mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 21385
Product name: GLYX 13
Purity: ≥98%
Packaging: 5mg
Price: $426
Updated: 2024/03/01

Tocris

Product number: 3406
Product name: GLYX13
Packaging: 1
Price: $150
Updated: 2021/12/16

TRC

Product number: G650020
Product name: GLYX-13
Packaging: 1mg
Price: $60
Updated: 2021/12/16

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GLYX 13 Chemical Properties,Usage,Production

Uses

Rapastinel is a novel antidepressant drug approved as an adjunctive therapy for the treatment of treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-orally active) amidated tetrapeptide (Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax ≈ 25%).The drug is a rapid-acting and long-lasting antidepressant as well as robust cognitive enhancer by virtue of its ability to both inhibit and enhance NMDA receptor-mediated signal transduction.

Uses

GLYX-13 is a long lasting and rapid acting antidepressant. Investigational drug for the treatment of depressive disoder.

Uses

GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor.

Biochem/physiol Actions

GLYX-13 is a glycine-site functional partial agonist (GFPA) selective modulator of the NMDA receptor (NMDAR). It is a brain penetrable tetrapeptide which acts as a positive allosteric modulator of the NMDA receptor, acting via the glycine site. GLYX-13 has been found to be a cognitive enhancer in learning models and is currently in clinical trials as an antidepressant.

storage

Store at -20°C

GLYX 13 Preparation Products And Raw materials

Raw materials

Preparation Products

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GLYX 13 Suppliers

China 117 India 1 United Kingdom 1 United States 14 Global 133

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

TargetMol Chemicals Inc.

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Country: United States
ProdList: 38631
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Aladdin Scientific

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Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

United States Biological

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Country: United States
ProdList: 6075
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ApexBio Technology

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ProdList: 6251
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Riedel-de Haen AG

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ProdList: 6773
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BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
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Cayman Chemical Company

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United States Biological

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MedChemExpress

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View Lastest Price from GLYX 13 manufacturers

Baoji Guokang Bio-Technology Co., Ltd.

Product: Rapastinel 117928-94-6
Price: US $240.00/g
Min. Order: 1g/Bag
Purity: 98%
Supply Ability: 10KG
Release date: 2021-06-04

Baoji Guokang Bio-Technology Co., Ltd.

Product: GLYX 13 117928-94-6
Price: US $238.00/g
Min. Order: 1g
Purity: 95%
Supply Ability: 100KG
Release date: 2021-06-05

hebei hongtan Biotechnology Co., Ltd

Product: GLYX-13 117928-94-6
Price: US $30.00/box
Min. Order: 1box
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-03-21

117928-94-6, GLYX 13Related Search:

Linezolid Teriparatide acetate RESIQUIMOD

L-ThreoninaMide, L-threonyl-L-prolyl-L-prolyl-

GLYX-13 trifluoroacetate

L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate

GLYX 13

Thr-Pro-Pro-Thr-NH2 trifluoroacetate

TPPT-amide trifluoroacetate

Rapastinel

GIYX-13

L-Threonyl-L-prolyl-L-prolyl-L-threoninamide

GLYX-13 trifluoroacetate,Rapastinel

GLYX13(Rapastinel)

(S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide

CS-1640

GLYX-13;GLYX 13;GLYX13

Rapastinel(GLYX-13)

UNII-6A1X56B95E

Rapastinel,GLYX-13,Thr-Pro-Pro-Thr-NH2, >99%

GLYX-13;GLYX13;GLYX 13;THR-PRO-PRO-THR-NH2

Thr-Pro-Pro-Thr-NH2

TPPT-amide

(2s)-1-[(2s)-1-[(2s,3r)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-n-[(2s,3r)-1-amino-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide

(S)-1-(L-threonyl-L-prolyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)pyrrolidine-2-carboxamide

NRX-1074 GLYX-13

Rapastinel (GLYX-13) acetate

GLYX 13 TFA

117928-94-6

C18H31N5O6