ChemicalBook > CAS DataBase List > 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile

Product Name: 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile
CAS No.: 76823-93-3
Chemical Name: 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile
Synonyms: TPN-BASE;Famotidine Impurity 12;Famotidine intermediate;Famotidine Cyanoethyl Impurity;CYANOETHYLTHIOMETHYL-2-THIAZOLYL GUANIDINE;4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINE;2-[4-(2-CYANOETHYLTHIO)METHYL]THIAZOLYL GUANIDINE;3-(2-Guanidino-4-thiazolylmethulthio)propinitrile;3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIONITRILE;3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE
CBNumber: CB4251891
Molecular Formula: C8H11N5S2
Formula Weight: 241.34
MOL File: 76823-93-3.mol

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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Property

Melting point:: 128-132 °C(lit.)
Boiling point:: 459.7±55.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 8.51±0.70(Predicted)
color: White to Beige
CAS DataBase Reference: 76823-93-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-43
Safety Statements: 22-24-37
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 546879
Product name: 2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Purity: 97%
Packaging: 25g
Price: $388.55
Updated: 2025/07/31

TRC

Product number: D416372
Product name: 3-[[[2-[(Diaminomethylene]amino-4-thiazolyl]thio]propionitrile
Packaging: 5G
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC21486
Product name: 2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Packaging: 25g
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC21486
Product name: 2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Packaging: 50g
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC21486
Product name: 2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Packaging: 100g
Price: $120
Updated: 2021/12/16

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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Famotidine intermediate.

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Preparation Products And Raw materials

Raw materials

Amidinothiourea 1,3-Dichloroacetone

Preparation Products

3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER

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View Lastest Price from 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile manufacturers

Qiuxian Baitai New Material Co., LTD

Product: 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 76823-93-3
Price: US $98.00/g
Min. Order: 100g
Purity: 99%
Supply Ability: 500ton/Month
Release date: 2021-10-25

76823-93-3, 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrileRelated Search:

Methyl 2-hydroxyethyl cellulose (2-Methoxyethyl)benzene Benzothiazole 3-Aminopropionitrile Fosthiazate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Dicyandiamide 2-Methyl-4-isothiazolin-3-one ISOMETHIOZIN N-DesaMinosulfonyl-N-cyano FaMotidine Famotidine EP Impurity A Sulfamide [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) FAMOTIDINE RELATED COMPOUND B 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

TPN-BASE

(4-(((2-Cyanoethyl)thio)methyl)-2-thia-zolyl)guanidine

[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-guanidin

N-[4-(2-CYANO-ETHYLSULFANYLMETHYL)-THIAZOL-2YL]-GUANIDINE

N-[4-[(2-CYANOETHYL)THIO]METHYL]-2THIAZOLYL]GUANIDINE

CYANOETHYLTHIOMETHYL-2-THIAZOLYL GUANIDINE

2-[4-(2-CYANOETHYLTHIO)METHYL]THIAZOLYL GUANIDINE

3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIONITRILE

2-[4-[(2-cyanoethylthio)methyl]-2-thiazolyl]guanidine

1-{4-[(2-Cyanoethyl)thiomethyl]thiazol-2-yl}guanidine

3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE

3-((2-Guanidino-4-thiazolyl)methyl thiopropanenitrile

3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE ,GB

4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINE

4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINEFAMOTIDINE HCL

3-(2-(diaminomethyleneamino)thiazol-4-ylmethylthio)propionitrile

(4-(((2YANOETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE

Famotidine Impurity 12

Famotidine intermediate

Famotidine Cyanoethyl Impurity

Guanidine, N-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-

3-(2-Guanidino-4-thiazolylmethulthio)propinitrile

3-(2-(diaminomethyleneamino)thiazol-4-yl)methylthio)propiono...

Guanidine,[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]- (9CI)

3-(((2-((Diaminomethyl) amino)-4-thiazolyl)-methyl) thio) propionitrile. (T.P.N. Base, an intermediate of Famotidine)

3-(2-(diaminomethyleneamino)thiazol-4-yl)methylthio)propiononitrile

76823-93-3

C8H11N5S2

C9H13N5S2

Building Blocks

Heterocyclic Building Blocks

Thiazoles

Building Blocks

Heterocyclic Building Blocks

Thiazoles

Heterocycles

Intermediates

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds

Building Blocks

C8 to C9

Chemical Synthesis

Heterocyclic Building Blocks