ChemicalBook > CAS DataBase List > 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile

Product Name
3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile
CAS No.
76823-93-3
Chemical Name
3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile
Synonyms
TPN-BASE;Famotidine Impurity 12;Famotidine intermediate;Famotidine Cyanoethyl Impurity;CYANOETHYLTHIOMETHYL-2-THIAZOLYL GUANIDINE;4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINE;2-[4-(2-CYANOETHYLTHIO)METHYL]THIAZOLYL GUANIDINE;3-(2-Guanidino-4-thiazolylmethulthio)propinitrile;3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIONITRILE;3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE
CBNumber
CB4251891
Molecular Formula
C8H11N5S2
Formula Weight
241.34
MOL File
76823-93-3.mol
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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Property

Melting point:
128-132 °C(lit.)
Boiling point:
459.7±55.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
8.51±0.70(Predicted)
color 
White to Beige
CAS DataBase Reference
76823-93-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
22-24-37
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
546879
Product name
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Purity
97%
Packaging
25g
Price
$158.8
Updated
2024/03/01
TRC
Product number
D416372
Product name
3-[[[2-[(Diaminomethylene]amino-4-thiazolyl]thio]propionitrile
Packaging
5G
Price
$180
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC21486
Product name
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Packaging
25g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC21486
Product name
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Packaging
50g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC21486
Product name
2-[4-(2-Cyanoethylthio)methyl]thiazolyl guanidine
Packaging
100g
Price
$120
Updated
2021/12/16
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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Famotidine intermediate.

3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Preparation Products And Raw materials

Raw materials

Amidinothiourea 1,3-Dichloroacetone

Preparation Products

3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER
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3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile Suppliers

Canada 2 China 76 Germany 1 India 10 Singapore 1 Switzerland 1 Ukraine 1 United Kingdom 4 United States 11 Global 107
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View Lastest Price from 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile manufacturers

Qiuxian Baitai New Material Co., LTD
Product
3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 76823-93-3
Price
US $98.00/g
Min. Order
100g
Purity
99%
Supply Ability
500ton/Month
Release date
2021-10-25

76823-93-3, 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrileRelated Search:

Methyl 2-hydroxyethyl cellulose (2-Methoxyethyl)benzene Benzothiazole 3-Aminopropionitrile Fosthiazate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Dicyandiamide 2-Methyl-4-isothiazolin-3-one ISOMETHIOZIN N-DesaMinosulfonyl-N-cyano FaMotidine Famotidine EP Impurity A Sulfamide [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) FAMOTIDINE RELATED COMPOUND B 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride

  • TPN-BASE
  • (4-(((2-Cyanoethyl)thio)methyl)-2-thia-zolyl)guanidine
  • [4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-guanidin
  • N-[4-(2-CYANO-ETHYLSULFANYLMETHYL)-THIAZOL-2YL]-GUANIDINE
  • N-[4-[(2-CYANOETHYL)THIO]METHYL]-2THIAZOLYL]GUANIDINE
  • CYANOETHYLTHIOMETHYL-2-THIAZOLYL GUANIDINE
  • 2-[4-(2-CYANOETHYLTHIO)METHYL]THIAZOLYL GUANIDINE
  • 3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIONITRILE
  • 2-[4-[(2-cyanoethylthio)methyl]-2-thiazolyl]guanidine
  • 1-{4-[(2-Cyanoethyl)thiomethyl]thiazol-2-yl}guanidine
  • 3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE
  • 3-((2-Guanidino-4-thiazolyl)methyl thiopropanenitrile
  • 3-(2-GUANIDINOTHIAZOL-4-YLMETHYLTHIO)PROPIOUITRILE ,GB
  • 4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINE
  • 4-[(2-CYANOETHYL)THIO]-2-THIAZOLYL]GUANIDINEFAMOTIDINE HCL
  • 3-(2-(diaminomethyleneamino)thiazol-4-ylmethylthio)propionitrile
  • (4-(((2YANOETHYL)THIO)METHYL)-2-THIAZOLYL)GUANIDINE
  • Famotidine Impurity 12
  • Famotidine intermediate
  • Famotidine Cyanoethyl Impurity
  • Guanidine, N-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-
  • 3-(2-Guanidino-4-thiazolylmethulthio)propinitrile
  • 3-(2-(diaminomethyleneamino)thiazol-4-yl)methylthio)propiono...
  • Guanidine,[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]- (9CI)
  • 3-(((2-((Diaminomethyl) amino)-4-thiazolyl)-methyl) thio) propionitrile. (T.P.N. Base, an intermediate of Famotidine)
  • 76823-93-3
  • C8H11N5S2
  • C9H13N5S2
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiazoles
  • Building Blocks
  • Heterocyclic Building Blocks
  • Thiazoles
  • Heterocycles
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Building Blocks
  • C8 to C9
  • Chemical Synthesis
  • Heterocyclic Building Blocks