1-Fluoro-cyclopropanecarboxylic acid
- Product Name
- 1-Fluoro-cyclopropanecarboxylic acid
- CAS No.
- 137081-41-5
- Chemical Name
- 1-Fluoro-cyclopropanecarboxylic acid
- Synonyms
- 1-Fluorocyclopropanecarboxylic;Fluorocyclopropanecarboxylic acid;1-Fluoro-cyclopropanecarboxylic acid;1-Fluorocyclopropane-1-carboxylicacid;Cyclopropanecarboxylic acid, 1-fluoro-;1-Fluoro-Cyclopropanecarboxylic Acid(WXFC0175)
- CBNumber
- CB42550053
- Molecular Formula
- C4H5FO2
- Formula Weight
- 104.08
- MOL File
- 137081-41-5.mol
1-Fluoro-cyclopropanecarboxylic acid Property
- Melting point:
- 63-67℃
- Boiling point:
- 120-125℃ (100 Torr)
- Density
- 1.36±0.1 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 56.6±22.6℃
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- 2.61±0.20(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C4H5FO2/c5-4(1-2-4)3(6)7/h1-2H2,(H,6,7)
- InChIKey
- NDCPERCVXDYEFU-UHFFFAOYSA-N
- SMILES
- C1(F)(C(O)=O)CC1
Safety
- Safety Statements
- 24/25
- RIDADR
- UN3261
- HS Code
- 29162090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F1254
- Product name
- 1-Fluorocyclopropanecarboxylic Acid
- Packaging
- 200MG
- Price
- $36
- Updated
- 2026/03/19
- Product number
- F1254
- Product name
- 1-Fluorocyclopropanecarboxylic Acid
- Packaging
- 1G
- Price
- $119
- Updated
- 2026/03/19
- Product number
- F588873
- Product name
- 1-Fluorocyclopropane-1-carboxylicacid
- Packaging
- 250mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- Z2303
- Product name
- 1-Fluoro-cyclopropane-1-carboxylicacid
- Packaging
- 10g
- Price
- $641
- Updated
- 2021/12/16
- Product number
- AS43504
- Product name
- 1-Fluorocyclopropane-1-carboxylic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $832
- Updated
- 2021/12/16
1-Fluoro-cyclopropanecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
1-Fluorocyclopropanecarboxylic acid is easy to react with metal ions, π-π and other non-covalent bonds, which is an important fragment for the construction of diversified organic structures; there is cyclopropane in its structure, which is easy to undergo nucleophilic substitution reactions.
Uses
1-Fluorocyclopropane-1-carboxylic acid
Synthesis
63141-10-6
137081-41-5
General procedure for the synthesis of 1-fluorocyclopropanecarboxylic acid from 1-fluorocyclopropylmethyl ketone: Bromine (14.8 g, 93 mmol) was slowly added to a solution of sodium hydroxide (12.36 g, 300 mmol) in water (50 mL) at below 10 °C. Subsequently, 1-(1-fluorocyclopropyl)ethanone (3.3 g, 30 mmol) was added. The reaction mixture was slowly cooled to below 0°C and then stirred at room temperature for 1 hour. Sodium metabisulfite was added until the solution became colorless. Ethyl acetate (50 mL) was added, and the aqueous phase was separated and acidified with hydrochloric acid (2 M) to pH 2. The aqueous phase was extracted with ethyl acetate (3 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated to give 1-fluorocyclopropanecarboxylic acid as a white solid (2.2 g, 66% yield).1H NMR (CDCl3, 400 MHz): δ 1.49-1.45 (m, 4H).
References
[1] Journal of Molecular Structure, 2004, vol. 695-696, p. 163 - 169
[2] Patent: US2014/107340, 2014, A1. Location in patent: Paragraph 0112
[3] Patent: US5126338, 1992, A
1-Fluoro-cyclopropanecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Fluoro-cyclopropanecarboxylic acid manufacturers
- Product
- 1-Fluoro-cyclopropanecarboxylic acid 137081-41-5
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-18
- Product
- 1-Fluoro-cyclopropanecarboxylic acid 137081-41-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-04-10
- Product
- 1-Fluoro-cyclopropanecarboxylic acid 137081-41-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-09