ChemicalBook > CAS DataBase List > 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile

Product Name
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
CAS No.
138401-24-8
Chemical Name
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
Synonyms
Irbint-A04;CyanoIrbesartan;4'-[(2-Butyl-4-oxo-1;Irbesartan Alkylation;Irbesartan IMpurity B;Irbesartan Impurity 12;Irbesartan Cyano IMpurity;He sand hydrocarbon compound;4'-[(2-Butyl-4-oxo-1,3-diazasp;diazaspiro[4.4]non-1-en-3-yl)methyl]-
CBNumber
CB4259312
Molecular Formula
C25H27N3O
Formula Weight
385.5
MOL File
138401-24-8.mol
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4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Property

Melting point:
95-97°C
Boiling point:
576.5±60.0 °C(Predicted)
Density 
1.15
vapor pressure 
0Pa at 20℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
Crystalline
pka
2.45±0.20(Predicted)
color 
White to Almost white
LogP
3.7 at 20℃ and pH7
Surface tension
72.5mN/m at 1.025mg/L and 20℃
CAS DataBase Reference
138401-24-8(CAS DataBase Reference)
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Safety

Hazard Codes 
N
Risk Statements 
50/53
Safety Statements 
60-61
RIDADR 
3077
HS Code 
2933.29.4300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4143
Product name
2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one
Purity
>97.0%(N)
Packaging
1g
Price
$78
Updated
2024/03/01
TCI Chemical
Product number
B4143
Product name
2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one
Purity
>97.0%(N)
Packaging
5g
Price
$270
Updated
2024/03/01
TRC
Product number
B693590
Product name
4''-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1''-Biphenyl]-2-carbonitrile
Packaging
1g
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB19496
Product name
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile
Packaging
1g
Price
$149.9
Updated
2021/12/16
AK Scientific
Product number
I709
Product name
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]biphenyl-2-carbonitrile
Packaging
5g
Price
$227
Updated
2021/12/16
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4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Chemical Properties,Usage,Production

Chemical Properties

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile is WHite Solid

Uses

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile is a butyldiazaspirononenone derivative used in the preparation of acetylcholinesterase inhibitors. An impurity found in Irbesartan (I751000).

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Suppliers

Americas 1 Canada 1 China 156 Europe 3 Germany 3 India 54 Japan 1 South Korea 1 United Kingdom 8 United States 23 Global 251
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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Adamas Reagent, Ltd.
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shchemsky@sina.com
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15527768850
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1791901229@qq.com
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China
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China Langchem Inc.
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0086-21-58956006
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0086-21-58956100
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China
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-4000505016 13380397412
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0755 28094224
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3001272453@qq.com
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China
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Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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010-65763397
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waley188@sohu.com
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China
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View Lastest Price from 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile 138401-24-8
Price
US $57.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100ton
Release date
2021-12-02
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile 138401-24-8
Price
US $16.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
23kg
Release date
2022-01-11
Career Henan Chemical Co
Product
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile 138401-24-8
Price
US $1.00/KG
Min. Order
1KG
Purity
40%-99%
Supply Ability
1000kg
Release date
2018-08-20

138401-24-8, 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrileRelated Search:

1-AMINO-1-CYCLOPENTANECARBOXAMIDE 3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2-[1-[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]pentan-2-yl]-1,3-diazaspiro[4.4]non-1-en-4-one Irbesartan IMpurity Irbesartan Impurity 15 Sodium Salt Irbesartan Impurity 4 1-[(2'-Cyano[1,1'-biphenyl]-4-yl)MethylaMino]-N-pentanoylcyclopentanecarboxaMide Irbesartan N--D-Glucuronide Irbesartan Irbesartan Impurity DeMethyl Irbesartan Irbesartan Impurity 14 IRBESARTAN RELATED COMPOUND A (25 MG) (1-PENTANOYLAMINO-CYCLOPENTANECARBOXYLIC ACID [2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-AMIDE) L-Serine methyl ester hydrochloride 2-Butyl-4-spirocyclopentane-2-imidazolin-5-one hydrochloride [1,1'-Biphenyl]-2-carboxamide, 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]- THIOGLYCOLIC ACID N-BUTYL ESTER Irbesartan 4'-Methyl-2-cyanobiphenyl

  • [1,1'-BIPHENYL]-2-CARBONITRILE, 4'-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-
  • [1,1'-BIPHENYL]-2-CARBONITRILE-4-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]
  • Irbesartan Alkylation
  • He sand hydrocarbon compound
  • 3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1
  • 4'-[(2-Butyl-4-oxo-1
  • Irbint-A04
  • Irbesartan Impurity 12
  • [1.1’-Biphenyl]-2-Carbonitrile-4-[(2-Butyl-4-Oxo-1.3- Diazaspiro[4.4]
  • 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
  • 4'-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]BIPHENYL-2-CARBONITRILE
  • 4'-[(2-N-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-[1,1'-BIPHENYL]-2-CARBONITRILE
  • [1.1'-Biphenyl]-2-carbonitrile-4-[(2-butyl-4-oxo-1.3-diazaspiro[4.4]non-1-en-3-y
  • 4'-[(2-Butyl-4-oxo-1,3-diazasp
  • 4-(2-butyl-1,3-diazaspiro-[4-4] no-1-en-3-yl-methyl)biphenyl-2-carbonitrile
  • 4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrile
  • [1,1'-Biphenyl]-2-carbonitrile,4'-[(2-butyl-4-oxo-1,3-
  • diazaspiro[4.4]non-1-en-3-yl)methyl]-
  • 2-Butyl-3-[[2'-(cyano)biphenyl-4-yl]Methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
  • 4-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl
  • Irbesartan IMpurity B
  • Irbesartan Cyano IMpurity
  • 5-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}Methyl)-2-phenylbenzonitrile
  • 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]Methyl]-1,3-diazaspiro[4,4]non-1-en-4-one
  • CyanoIrbesartan
  • 2-[4-[(8-butyl-6-oxo-7,9-diazaspiro[4.4]non-8-en-7-yl)methyl]phenyl]benzonitrile
  • Irbesartan impurity 1/Irbesartan Cyano Impurity/4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]biphenyl-2-carbonitrile
  • 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one &gt
  • 4'-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-(1,1'-BIPHENYL)-2-CARBONITRILE/138401-24-8
  • 1-[2'-cyanobipheynl-4-yl)methyl]-2n-butyl-4--spirocyclopentane-2-imidazolin-5-one
  • 2-n-Butyl-3-(2-cyanobiphenyl-4yl)methyl-1,3-diaza-spiro[4,4]non-1-en-4-one
  • 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]b...
  • C25H27N3O 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile 138401-24-8
  • 4' -[(2-Buty1-4- oxo-1,3-diazaspiro[4.4]non-1-en-3yl) methylbiphenyl-2- carbonitrile
  • 4'-[(2-butyl-4-oxo-1,3-diazaspiro [4,4] non-1-en-3-yl) methyl [1,1' - bis phenyl]-2-carbonitrile
  • 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one, ≥ 97.0%
  • 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one
  • 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile
  • [1,1'-Biphenyl]-2-carbonitrile,4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]
  • 2-Butyl-3-[[2'-(cyano)biphenyl-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
  • Irbesartan Cyano Impurity 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3- yl)methyl]biphenyl-2-carbonitrile
  • 138401-24-8
  • 138401-24-6
  • C25H27N3O
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chemical intermediate for Sartan
  • INTERMEDIATESOF
  • Irbesartan
  • (intermediate of irbesartan)