2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride

ChemicalBook > CAS DataBase List > 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride

Product Name: 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
CAS No.: 199864-86-3
Chemical Name: 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
Synonyms: MT 500 Hydrochloride;RS 127445 hydrochloride NEW;4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine;2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride;2-AMino-4-(4-fluoronaphth-1-yl)-6-isopropylpyriMidine Monohydrochloride;4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine monohydrochloride;2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
CBNumber: CB42609717
Molecular Formula: C17H17ClFN3
Formula Weight: 317.7883832
MOL File: 199864-86-3.mol

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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Property

Melting point:: 158 °C
storage temp.: 2-8°C
solubility: DMSO: ≥20mg/mL
form: powder
color: white to tan

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Safety

Hazard Codes: T
Risk Statements: 25-36
Safety Statements: 26-45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HS Code: 2933.59.5300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R2533
Product name: RS-127445 hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $129
Updated: 2024/03/01

Sigma-Aldrich

Product number: R2533
Product name: RS-127445 hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $500
Updated: 2024/03/01

TCI Chemical

Product number: R0221
Product name: RS-127445 Hydrochloride
Packaging: 10MG
Price: $211
Updated: 2024/03/01

TCI Chemical

Product number: R0221
Product name: RS-127445 Hydrochloride
Packaging: 50MG
Price: $756
Updated: 2024/03/01

Cayman Chemical

Product number: 23451
Product name: RS 127445 (hydrochloride)
Purity: ≥98%
Packaging: 1 mg
Price: $32
Updated: 2024/03/01

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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Chemical Properties,Usage,Production

Uses

RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.

storage

Desiccate at +4°C

2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Suppliers

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199864-86-3, 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, MonohydrochlorideRelated Search:

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