ChemicalBook > CAS DataBase List > 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
- Product Name
- 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
- CAS No.
- 199864-86-3
- Chemical Name
- 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
- Synonyms
- MT 500 Hydrochloride;RS 127445 hydrochloride NEW;4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine;2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride;2-AMino-4-(4-fluoronaphth-1-yl)-6-isopropylpyriMidine Monohydrochloride;4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine monohydrochloride;2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
- CBNumber
- CB42609717
- Molecular Formula
- C17H17ClFN3
- Formula Weight
- 317.7883832
- MOL File
- 199864-86-3.mol
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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Property
- Melting point:
- 158 °C
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- color
- white to tan
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- R2533
- Product name
- RS-127445 hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $129
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- R2533
- Product name
- RS-127445 hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $500
- Updated
- 2024/03/01
TCI Chemical
- Product number
- R0221
- Product name
- RS-127445 Hydrochloride
- Packaging
- 10MG
- Price
- $211
- Updated
- 2024/03/01
TCI Chemical
- Product number
- R0221
- Product name
- RS-127445 Hydrochloride
- Packaging
- 50MG
- Price
- $756
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23451
- Product name
- RS 127445 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1 mg
- Price
- $32
- Updated
- 2024/03/01
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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Chemical Properties,Usage,Production
Uses
RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.
storage
Desiccate at +4°C
2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride Suppliers
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