1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-

Product Name: 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
CAS No.: 811442-85-0
Chemical Name: 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
Synonyms: Biotin-PEG1-NH2;Biotin-PEG1-amine;(+)-Biotin-PEG1-amine;N-[2-(2-Aminoethoxy)ethyl]-biotinamide;1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-;N-(2-(2-Aminoethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
CBNumber: CB42638966
Molecular Formula: C14H26N4O3S
Formula Weight: 330.45
MOL File: 811442-85-0.mol

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1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- Property

storage temp.: 2-8°C, protect from light
solubility: good in water, DMSO, DMF
form: Solid
color: White to off-white
Appearance: white solid
InChI: InChI=1S/C14H26N4O3S/c15-5-7-21-8-6-16-12(19)4-2-1-3-11-13-10(9-22-11)17-14(20)18-13/h10-11,13H,1-9,15H2,(H,16,19)(H2,17,18,20)/t10-,11-,13-/m0/s1
InChIKey: MJCKXPHJERSYIX-GVXVVHGQSA-N
SMILES: C1(=O)N[C@]2([H])[C@H](CCCCC(NCCOCCN)=O)SC[C@]2([H])N1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Acrotein

Product number: B-1334
Product name: N-[2-(2-Aminoethoxy)ethyl]-biotinamide
Purity: 97%
Packaging: 1g
Price: $550
Updated: 2021/12/16

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1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- Chemical Properties,Usage,Production

Description

Biotin-PEG2-amine is a diethylene glycol (PEG2) based bifunctional molecule containing biotin and a primary amino group. The reagent makes it possible to label various biomolecules (such as DNA, oligonucleotides, and proteins) with biotin by reacting the amino group with NHS esters or carboxylic acids in the presence of EDC or HATU. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection.

A short PEG2-linker separates the biotin residue from the target molecule, ensuring efficient binding to avidin or streptavidin. The linker also increases the compound’s water solubility, thereby facilitating bioconjugation.

Uses

Biotin-PEG1-NH2 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- Suppliers

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View Lastest Price from 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG1-amine 811442-85-0
Price: US $0.00/g
Min. Order: 1g
Purity: >95.00%
Supply Ability: 1g
Release date: 2024-03-30

811442-85-0, 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-Related Search:

Biotin-PEG1-NHS ester Biotin-PEG5-azide N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Biotin-PEG1-COOH N-(2-(2-Azidoethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 2-(biotinylamido)ethanol Biotin-PEG1-hydrazide Biotin-PEG5-Amine N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Biotin-PEG4-N3 Biotin-PEG<sub>4</sub>-Azide N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine Biotin-PEG3-N3 Biotin-PEG4-Alkyne Biotin-PEG1-oxyamine HCl salt Biotin-PEG1-SH Biotin-PEG1-TFP

1H-Thieno[3,4-d]iMidazole-4-pentanaMide, N-[2-(2-aMinoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-

N-(2-(2-Aminoethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

N-[2-(2-Aminoethoxy)ethyl]-biotinamide

Biotin-PEG1-NH2

Biotin-PEG1-amine

(+)-Biotin-PEG1-amine

811442-85-0

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