11107B

Product Name: 11107B
CAS No.: 445493-23-2
Chemical Name: 11107B
Synonyms: 11107B;11107AD;PLADIENOLIDE B;SDOUORKJIJYJNW-VGQSKDSZSA-N;(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one;Oxacyclododec-9-en-2-one, 8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyl-, (4R,7R,8S,9E,11S,12S)-
CBNumber: CB42666916
Molecular Formula: C30H48O8
Formula Weight: 536.7
MOL File: 445493-23-2.mol

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11107B Property

Boiling point:: 673.8±55.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form: A clear film
pka: 13.98±0.70(Predicted)
color: Colorless to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16538
Product name: Pladienolide B
Purity: ≥95%
Packaging: 100μg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 16538
Product name: Pladienolide B
Purity: ≥95%
Packaging: 500μg
Price: $410
Updated: 2024/03/01

Tocris

Product number: 6070
Product name: PladienolideB
Purity: ≥95%(HPLC)
Packaging: 500U
Price: $371
Updated: 2021/12/16

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11107B Chemical Properties,Usage,Production

Uses

Pladienolide B is the major analogue of a family of macrocyclic lactones isolated from Streptomyces platensis. Pladienolide B is a highly potent inhibitor of both hypoxia signals and cancer cell proliferation. Pladienolide B binds to SF3b complex blocking the spliceosome.

Uses

Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome.

storage

Store at -20°C

11107B Preparation Products And Raw materials

Raw materials

Preparation Products

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11107B Suppliers

China 22 United Kingdom 2 United States 3 USA 1 Global 28

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
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Shanghai fuxiang biotechnology co., ltd

Tel: 13611719524
Email: 2674347328@qq.com
Country: China
ProdList: 57
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9804
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
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Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32159
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: wulan@absin.cn
Country: China
ProdList: 24731
Advantage: 58

445493-23-2, 11107BRelated Search:

11107AD

11107B

PLADIENOLIDE B

SDOUORKJIJYJNW-VGQSKDSZSA-N

(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one

Oxacyclododec-9-en-2-one, 8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyl-, (4R,7R,8S,9E,11S,12S)-

445493-23-2