GLPG 0492

Product Name: GLPG 0492
CAS No.: 1215085-92-9
Chemical Name: GLPG 0492
Synonyms: GLPG 0492;GLPG-0492 (GLPG0492);4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile;Benzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-
CBNumber: CB42667074
Molecular Formula: C19H14F3N3O3
Formula Weight: 389.33
MOL File: 1215085-92-9.mol

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GLPG 0492 Property

Melting point:: 66 - 71°C
Boiling point:: 544.0±60.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Ethanol (Slightly, Sonicated)
pka: 13.50±0.10(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29938
Product name: GLPG0492
Packaging: 1mg
Price: $384
Updated: 2024/03/01

TRC

Product number: G411000
Product name: GLPG-0492
Packaging: 2.5mg
Price: $425
Updated: 2021/12/16

TRC

Product number: G411000
Product name: GLPG-0492
Packaging: 25mg
Price: $2360
Updated: 2021/12/16

AK Scientific

Product number: 3883DP
Product name: 4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Packaging: 1mg
Price: $525
Updated: 2021/12/16

Crysdot

Product number: CD31004258
Product name: GLPG0492
Purity: 98+%
Packaging: 50mg
Price: $1042
Updated: 2021/12/16

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GLPG 0492 Chemical Properties,Usage,Production

Description

GLPG0492 is a selective androgen receptor modulator (SARM). It activates the androgen receptor in a transactivation assay (EC₅₀ = 12 nM in HeLa cells expressing the human receptor). GLPG0492 (10 mg/kg per day) increases levator ani muscle weight, a marker of anabolic activity, but has no effect on ventral prostate weight, a marker of androgenic activity, in castrated rats. It increases twitch tension in isolated diaphragm strips, as well as increases the total distance run in a treadmill test and decreases gastrocnemius muscle fibrosis in the exercised-mdx mouse model of muscular dystrophy when administered at a dose of 30 mg/kg. GLPG0492 also reverses immobilization-induced muscle atrophy in a mouse model of hindlimb immobilization.

Uses

GLPG-0492 is a non-steroidal Selective Androgen Receptor Modulator (SARM), which can be used to reduce muscle loss while sparing reproductive tissues.

GLPG 0492 Preparation Products And Raw materials

Raw materials

Preparation Products

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GLPG 0492 Suppliers

China 35 India 2 United States 9 Global 46

Yichang Chanod Biomedical Technology Co,LTD

Tel: 0717-6855399 15377615856
Email: sales@sndswyy.cn
Country: China
ProdList: 78
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Birdo (Shanghai) Medical Technology Co., Ltd.

Tel: 021-58099077
Fax: -
Email: sales@birdochem.com
Country: China
ProdList: 185
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

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View Lastest Price from GLPG 0492 manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd

Product: GLPG-0492 1215085-92-9
Price: US $0.00/gram
Min. Order: 10gram
Purity: 99% min
Supply Ability: 20 tons
Release date: 2022-10-20

Nantong Guangyuan Chemicl Co,Ltd

Product: GLPG0492 1215085-92-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-11-30

Hebei Xinsheng New Material Technology Co., LTD.

Product: GLPG 0492 1215085-92-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 20tons
Release date: 2023-09-01

1215085-92-9, GLPG 0492Related Search:

GLPG 0492

GLPG-0492 (GLPG0492)

Benzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-

4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile

1215085-92-9