Optovin

Product Name: Optovin
CAS No.: 348575-88-2
Chemical Name: Optovin
Synonyms: CS-1131;Optovin;Oprovin;Optovin (mixture of isomers);5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone;5-((2,5-Dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one;4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-
CBNumber: CB42708133
Molecular Formula: C15H13N3OS2
Formula Weight: 315.41
MOL File: 348575-88-2.mol

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Optovin Property

Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in DMSO (up to 30 mg/ml)
pka: 7.65±0.50(Predicted)
form: solid
color: Tan
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14851
Product name: Optovin
Purity: ≥98%
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 14851
Product name: Optovin
Purity: ≥98%
Packaging: 10mg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 14851
Product name: Optovin
Purity: ≥98%
Packaging: 25mg
Price: $317
Updated: 2024/03/01

Cayman Chemical

Product number: 14851
Product name: Optovin
Purity: ≥98%
Packaging: 50mg
Price: $553
Updated: 2024/03/01

Tocris

Product number: 4901
Product name: Optovin
Purity: ≥99%(HPLC)
Packaging: 50
Price: $767
Updated: 2021/12/16

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Optovin Chemical Properties,Usage,Production

Description

Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50?= 2 μM) and mice,?in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1

Uses

Optovin activates human TRPA1 via structure-dependent photochemistry.

Definition

ChEBI: Optovin is a member of the class of thiazolidinone that is rhodanine in which the two methylene hydrogens have been replaced by a 2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl]methylidene group. A TRPA1 ligand that can be reversibly photoactivated. It has a role as a TRPA1 channel agonist. It is a member of pyrroles, a member of pyridines, an olefinic compound and a thiazolidinone. It is functionally related to a rhodanine.

storage

Store at +4°C

References

1) Kokel?et al. (2013),?Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol.,?9?257

Optovin Preparation Products And Raw materials

Raw materials

Preparation Products

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Optovin Suppliers

China 65 India 1 The Netherlands 1 United Kingdom 1 United States 12 Global 80

BOC Sciences

Tel: 16314854226
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Country: United States
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Target molecule Corp.

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Musechem

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
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Advantage: 58

InvivoChem

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Fax: 708-557-7486
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Cckinase, Inc.

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Aladdin Scientific

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Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
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TargetMol Chemicals Inc.

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ApexBio Technology

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Focus Biomolecules

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Cayman Chemical Company

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United States Biological

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View Lastest Price from Optovin manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Optovin 348575-88-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Optovin 348575-88-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 4-?Thiazolidinone, 5-?[[2,?5-?dimethyl-?1-?(3-?pyridinyl)?-?1H-?pyrrol-?3-?yl]?methylene]?-?2-?thioxo- 348575-88-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-23

348575-88-2, OptovinRelated Search:

A 967079 Minoxidil 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid Isradipine

Optovin

CS-1131

4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-

5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone

Oprovin

5-((2,5-Dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one

Optovin (mixture of isomers)

348575-88-2

Inhibitors