MK-4827 (R-enantioMer)

Product Name: MK-4827 (R-enantioMer)
CAS No.: 1038915-58-0
Chemical Name: MK-4827 (R-enantioMer)
Synonyms: (R)-Niraparib;ent-Niraparib;ent-Nirapanib;Niraparib Impurity;Niraparib Impurity 13;Niraparib Impurity 51;MK-4827 (R-enantioMer);Niraparib R-enantiomer;R isomer of MK-4827, Niraparib;(R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE
CBNumber: CB42716288
Molecular Formula: C19H20N4O
Formula Weight: 320.39
MOL File: 1038915-58-0.mol

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MK-4827 (R-enantioMer) Property

Boiling point:: 463.6±45.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 32 mg/mL (99.88 mM)
pka: 15.36±0.30(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: N481410
Product name: ent-Niraparib
Packaging: 500mg
Price: $2230
Updated: 2021/12/16

ChemScene

Product number: CS-3085
Product name: NiraparibR-enantiomer
Purity: 99.50%
Packaging: 5mg
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-3085
Product name: NiraparibR-enantiomer
Purity: 99.50%
Packaging: 10mg
Price: $380
Updated: 2021/12/16

ChemScene

Product number: CS-3085
Product name: NiraparibR-enantiomer
Purity: 99.50%
Packaging: 50mg
Price: $990
Updated: 2021/12/16

Crysdot

Product number: CD00013477
Product name: (R)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
Purity: 97%
Packaging: 1g
Price: $3294
Updated: 2021/12/16

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MK-4827 (R-enantioMer) Chemical Properties,Usage,Production

Uses

ent-Niraparib is an isomer of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Definition

ChEBI: 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an antineoplastic agent.

MK-4827 (R-enantioMer) Preparation Products And Raw materials

Raw materials

Preparation Products

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MK-4827 (R-enantioMer) Suppliers

China 28 India 1 United States 6 Global 35

SPIRO PHARMA

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Career Henan Chemica Co

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View Lastest Price from MK-4827 (R-enantioMer) manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: (R)-Niraparib 1038915-58-0
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-05-07

1038915-58-0, MK-4827 (R-enantioMer)Related Search:

Niraparib Niraparib tosylate MK-4827 (tosylate) (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide

MK-4827 (R-enantioMer)

Niraparib Impurity

R isomer of MK-4827, Niraparib

(R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE

Niraparib R-enantiomer

2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide

ent-Niraparib

2H-Indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]-

poly ADP ribose polymerase,Inhibitor,Niraparib (R enantiomer),PARP,Niraparib (Renantiomer),Niraparib (R-enantiomer),inhibit

(R)-Niraparib

Niraparib Impurity 13

ent-Nirapanib

Niraparib Impurity 51

1038915-58-0