MK-4827 (R-enantioMer)

Product Name: MK-4827 (R-enantioMer)
CAS No.: 1038915-58-0
Chemical Name: MK-4827 (R-enantioMer)
Synonyms: (R)-Niraparib;ent-Niraparib;ent-Nirapanib;Niraparib Impurity;Niraparib Impurity 13;Niraparib Impurity 51;MK-4827 (R-enantioMer);Niraparib R-enantiomer;R isomer of MK-4827, Niraparib;Niraparib R-enantiomer p-tosylate
CBNumber: CB42716288
Molecular Formula: C19H20N4O
Formula Weight: 320.39
MOL File: 1038915-58-0.mol

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MK-4827 (R-enantioMer) Property

Boiling point:: 463.6±45.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 32 mg/mL (99.88 mM)
pka: 15.36±0.30(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H340May cause genetic defects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: N481410
Product name: ent-Niraparib
Packaging: 500mg
Price: $2230
Updated: 2021/12/16

ChemScene

Product number: CS-3085
Product name: NiraparibR-enantiomer
Purity: 99.50%
Packaging: 5mg
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-3085
Product name: NiraparibR-enantiomer
Purity: 99.50%
Packaging: 10mg
Price: $380
Updated: 2021/12/16

ChemScene

Product number: CS-3085
Product name: NiraparibR-enantiomer
Purity: 99.50%
Packaging: 50mg
Price: $990
Updated: 2021/12/16

Crysdot

Product number: CD00013477
Product name: (R)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
Purity: 97%
Packaging: 1g
Price: $3294
Updated: 2021/12/16

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MK-4827 (R-enantioMer) Chemical Properties,Usage,Production

Uses

ent-Niraparib is an isomer of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Definition

ChEBI: 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an antineoplastic agent.

IC 50

PARP-1: 2.4 nM (IC₅₀)

MK-4827 (R-enantioMer) Preparation Products And Raw materials

Raw materials

Preparation Products

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MK-4827 (R-enantioMer) Suppliers

China 40 India 1 United States 6 Global 47

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7440
Advantage: 65

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
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TaiChem Taizhou Limited

Tel: 052386810091
Email: zcwy9518@yeah.net
Country: China
ProdList: 3917
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
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Amadis Chemical Company Limited

Tel: 571-89925085
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Email: sales@amadischem.com
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Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
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Jiangsu yize medical technology co. LTD

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Email: 3394205705@qq.com
Country: China
ProdList: 1751
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
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InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30227
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View Lastest Price from MK-4827 (R-enantioMer) manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: (R)-Niraparib 1038915-58-0
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-05-07

1038915-58-0, MK-4827 (R-enantioMer)Related Search:

(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide Niraparib Niraparib tosylate MK-4827 (tosylate)

MK-4827 (R-enantioMer)

Niraparib Impurity

R isomer of MK-4827, Niraparib

(R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE

Niraparib R-enantiomer

2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide

ent-Niraparib

2H-Indazole-7-carboxamide, 2-[4-(3R)-3-piperidinylphenyl]-

poly ADP ribose polymerase,Inhibitor,Niraparib (R enantiomer),PARP,Niraparib (Renantiomer),Niraparib (R-enantiomer),inhibit

(R)-Niraparib

Niraparib Impurity 13

ent-Nirapanib

Niraparib Impurity 51

Niraparib R-enantiomer p-tosylate

Niraparib (R-enantiomer), 10 mM in DMSO

1038915-58-0