(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
- Product Name
- (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
- CAS No.
- 909725-64-0
- Chemical Name
- (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
- Synonyms
- W140;W140 (TFA);(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt);(S)-3-AMINO-4-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W140
- CBNumber
- CB42720643
- Molecular Formula
- C18H28F3N2O6P
- Formula Weight
- 456.4
- MOL File
- 909725-64-0.mol
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Property
- storage temp.
- Store at -20°C
- solubility
- Ethanol: 0.15 mg/ml
- form
- A crystalline solid
N-Bromosuccinimide Price
- Product number
- 10009110
- Product name
- W140 (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $78
- Updated
- 2024/03/01
- Product number
- 10009110
- Product name
- W140 (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $146
- Updated
- 2024/03/01
- Product number
- 10009110
- Product name
- W140 (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $614
- Updated
- 2024/03/01
- Product number
- 10009110
- Product name
- W140 (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $1071
- Updated
- 2024/03/01
- Product number
- 3145EL
- Product name
- [(3S)-3-Amino-4-(3-hexylanilino)-4-oxobutyl]phosphonicacid;2,2,2-trifluoroaceticacid
- Packaging
- 1mg
- Price
- $262
- Updated
- 2021/12/16
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Chemical Properties,Usage,Production
Description
W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 .1 It only weakly binds to S1P1 (Ki = 4.6 μM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.1,2
Uses
W140 (TFA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
References
1. Sanna, M.G., Wang, S.K., Gonzalez-Cabrera, P.J., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo Nat. Chem. Biol. 2(8),434-441(2006).
2. Li, C., Chi, X.X., Xie, W., et al. Sphingosine 1-
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Suppliers
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