ChemicalBook > CAS DataBase List > (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)

Product Name
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
CAS No.
909725-64-0
Chemical Name
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
Synonyms
W140;W140 (TFA);(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt);(S)-3-AMINO-4-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W140
CBNumber
CB42720643
Molecular Formula
C18H28F3N2O6P
Formula Weight
456.4
MOL File
909725-64-0.mol
More
Less

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Property

storage temp. 
Store at -20°C
solubility 
Ethanol: 0.15 mg/ml
form 
A crystalline solid
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
10009110
Product name
W140 (trifluoroacetate salt)
Purity
≥95%
Packaging
500μg
Price
$78
Updated
2024/03/01
Cayman Chemical
Product number
10009110
Product name
W140 (trifluoroacetate salt)
Purity
≥95%
Packaging
1mg
Price
$146
Updated
2024/03/01
Cayman Chemical
Product number
10009110
Product name
W140 (trifluoroacetate salt)
Purity
≥95%
Packaging
5mg
Price
$614
Updated
2024/03/01
Cayman Chemical
Product number
10009110
Product name
W140 (trifluoroacetate salt)
Purity
≥95%
Packaging
10mg
Price
$1071
Updated
2024/03/01
AK Scientific
Product number
3145EL
Product name
[(3S)-3-Amino-4-(3-hexylanilino)-4-oxobutyl]phosphonicacid;2,2,2-trifluoroaceticacid
Packaging
1mg
Price
$262
Updated
2021/12/16
More
Less

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Chemical Properties,Usage,Production

Description

W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 .1 It only weakly binds to S1P1 (Ki = 4.6 μM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.1,2

References

1. Sanna, M.G., Wang, S.K., Gonzalez-Cabrera, P.J., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo Nat. Chem. Biol. 2(8),434-441(2006).
2. Li, C., Chi, X.X., Xie, W., et al. Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor J. Neurophysiol. 108(5),1473-1483(2012).

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Suppliers

China 14 United States 4 Global 18
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Creative Enzymes
Tel
1-516-855-7709
Fax
1-631-938-8127
Email
info@creative-enzymes.com
Country
United States
ProdList
8748
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Creative Enzymes
Tel
--
Fax
--
Email
info@creative-enzymes.com
Country
United States
ProdList
6057
Advantage
58

909725-64-0, (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)Related Search:

BenzenesulfonaMide, 4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]- N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE W-5 HYDROCHLORIDE W123 Exclusive N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE [(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)

  • (S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
  • (S)-3-AMINO-4-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W140
  • W140
  • W140 (TFA)
  • 909725-64-0