(METHYLTHIO)ACETIC ACID Property

Melting point:

13-14 °C(lit.)

Boiling point:

130-131 °C27 mm Hg(lit.)

Density 

1.219 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.495(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

form 

Liquid

pka

3.66(at 25℃)

Specific Gravity

1.2241.219

color 

Clear colorless to pale yellow

Sensitive 

Stench

BRN 

1740201

LogP

0.655 (est)

CAS DataBase Reference

2444-37-3(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3334

WGK Germany 

3

Hazard Note 

Irritant/Stench

HazardClass 

IRRITANT

HS Code 

29309090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

(METHYLTHIO)ACETIC ACID Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to pale yellow liquid

Uses

(Methylthio)acetic acid may be used in the synthesis of (5S,6S,8S)-8-acetoxy-6-(3,4-methylenedioxyphenyl)-1-[(methylthio)-acetyl]-1-azaspiro[4.4]nonane.

Definition

ChEBI: (methylthio)acetic acid is a sulfur-containing carboxylic consisting of thioglycolic acid carrying an S-methyl substituent. It has a role as a xenobiotic metabolite. It is a sulfur-containing carboxylic acid, a monocarboxylic acid and a methyl sulfide. It is functionally related to a thioglycolic acid. It is a conjugate acid of a (methylthio)acetate.

General Description

Formation of complexes of methyl thioacetate and copper(II) has been investigated. (Methylthio)acetic acid is an irreversible inhibitor of sarcosine oxidase and is effective in preventing the complete enzyme inactivation during modification.