ChemicalBook > CAS DataBase List > 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

Product Name
4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
CAS No.
420092-79-1
Chemical Name
4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
Synonyms
SW155246;SW155246 >=98% (HPLC);4-chloro-N-(4-hydroxynaphthalen- 1-yl)-3-nitrobenzenesulfonamide;4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide;Benzenesulfonamide, 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-;SW 155246,cancer,hDNMT1,DNMTs,DNMT1 inhibitor,SW155246,Inhibitor,SW-155246,inhibit,mDNMT3A,DNA MTases,DNA Methyltransferase
CBNumber
CB42751098
Molecular Formula
C16H11ClN2O5S
Formula Weight
378.79
MOL File
420092-79-1.mol
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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Property

storage temp. 
2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
color 
white to light brown
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1136
Product name
SW155246
Purity
≥98% (HPLC)
Packaging
5mg
Price
$105
Updated
2022/05/15
Sigma-Aldrich
Product number
SML1136
Product name
SW155246
Purity
≥98% (HPLC)
Packaging
25mg
Price
$423
Updated
2022/05/15
Cayman Chemical
Product number
21865
Product name
SW155246
Purity
≥98%
Packaging
1mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
21865
Product name
SW155246
Purity
≥98%
Packaging
5mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
21865
Product name
SW155246
Purity
≥98%
Packaging
10mg
Price
$172
Updated
2024/03/01
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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Chemical Properties,Usage,Production

Description

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.

4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Suppliers

China 39 United Kingdom 1 United States 5 Global 45
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87

420092-79-1, 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamideRelated Search:

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide 2-butylsulfinyl-4-phenyl-6-thiophen-2-ylthieno[5,4-b]pyridin-3-amine SW076956

  • 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
  • SW155246
  • Benzenesulfonamide, 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-
  • SW155246 >=98% (HPLC)
  • 4-chloro-N-(4-hydroxynaphthalen- 1-yl)-3-nitrobenzenesulfonamide
  • SW 155246,cancer,hDNMT1,DNMTs,DNMT1 inhibitor,SW155246,Inhibitor,SW-155246,inhibit,mDNMT3A,DNA MTases,DNA Methyltransferase
  • 420092-79-1