ChemicalBook > CAS DataBase List > 2,2,5-Trimethyl-1,3-dioxane-4,6-dione

2,2,5-Trimethyl-1,3-dioxane-4,6-dione

Product Name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
CAS No.
3709-18-0
Chemical Name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Synonyms
CHEMPACIFIC 41980;METHYL MELDRUM'S ACID;CYCL-ISOPROPYLIDENE METHYLMALONATE;2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE;1,3-DIOXANE-4,6-DIONE, 2,2,5-TRIMETHYL;2,2,5-Trimethyl-1,3-dioxane-4,6-dione C;2,2,5-Trimethyl-1,3-Dioxane-4,6-Dione 98%;(2S)-2-amino-3-(3-thiophenyl)propanoic acid;METHYLMALONIC ACID CYCLIC ISOPROPYLIDENE ESTER;Methyl MeldruM's acid,2,2,5-TriMethyl-1,3-dioxane-4,6-dione
CBNumber
CB4277839
Molecular Formula
C7H10O4
Formula Weight
158.15
MOL File
3709-18-0.mol
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2,2,5-Trimethyl-1,3-dioxane-4,6-dione Property

Melting point:
111-114 °C(lit.)
Boiling point:
203.22°C (rough estimate)
Density 
1.1229 (rough estimate)
refractive index 
1.4610 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Methanol
form 
Solid
pka
13.14±0.40(Predicted)
color 
White to Off-White
BRN 
124044
InChIKey
KJMCAXYHYPDRAV-UHFFFAOYSA-N
CAS DataBase Reference
3709-18-0(CAS DataBase Reference)
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
10-21
HS Code 
29171990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
210153
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Purity
97%
Packaging
25g
Price
$268
Updated
2024/03/01
TRC
Product number
T796215
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Packaging
25g
Price
$85
Updated
2021/12/16
AK Scientific
Product number
J94384
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Packaging
5g
Price
$35
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019174
Product name
2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE
Purity
95.00%
Packaging
25G
Price
$1229.73
Updated
2021/12/16
Ambeed
Product number
A442437
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Purity
97%
Packaging
1g
Price
$6
Updated
2021/12/16
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2,2,5-Trimethyl-1,3-dioxane-4,6-dione Chemical Properties,Usage,Production

Chemical Properties

White to slightly pink crystalline powder

Uses

2,2,5-Trimethyl-1,3-dioxane-4,6-dione is used as a reagent in the synthesis of 3'',4''-bis-difluoromethoxycinnamoylanthranilate (FT061) which is an orally-active antifibrotic agent that reduces albuminuria in rat models of progressive diabetic nephropathy.

Uses

2,2,5-Trimethyl-1,3-dioxane-4,6-dione was used for trapping the adduct formed during the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates.

General Description

X-ray irradiated single crystals of 2,2,5-trimethyl-1,3-dioxane-4,6-dione have been investigated by electron spin resonance (ESR), electron nuclear double resonance (ENDOR) and electron-electron double resonance (ELDOR) spectra.

2,2,5-Trimethyl-1,3-dioxane-4,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,2,5-Trimethyl-1,3-dioxane-4,6-dione manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,2,5-Trimethyl-1,3-dioxane-4,6-dione 3709-18-0
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-19
Career Henan Chemical Co
Product
2,2,5-Trimethyl-1,3-dioxane-4,6-dione 3709-18-0
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-23

3709-18-0, 2,2,5-Trimethyl-1,3-dioxane-4,6-dioneRelated Search:


  • CHEMPACIFIC 41980
  • CYCL-ISOPROPYLIDENE METHYLMALONATE
  • METHYLMALONIC ACID CYCLIC ISOPROPYLIDENE ESTER
  • METHYL MELDRUM'S ACID
  • 2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE
  • 1,3-DIOXANE-4,6-DIONE, 2,2,5-TRIMETHYL
  • 2-METHYLCYCLOPROPANECARBOXYLIC ACID, 98% , MIXTURE OF CIS AND TRANS
  • 2,2,5-Trimethyl-1,3-Dioxane-4,6-Dione 98%
  • 2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE(METHYL MELDRUM''S ACID)
  • cycl-Isopropylidene methylmalonate, Methyl Meldrum’s acid
  • Methyl MeldruM's acid,2,2,5-TriMethyl-1,3-dioxane-4,6-dione
  • cycl-Isopropylidene methylmalonate, Methyl Meldrums acid, Methylmalonic acid cyclic isopropylidene ester
  • Methyl Meldrums acid, Methylmalonic acid cyclic isopropylidene ester
  • (2S)-2-amino-3-(3-thiophenyl)propanoic acid
  • 2,2,5-Trimethyl-1,3-dioxane-4,6-dione C
  • 3709-18-0
  • C7H10O4
  • Building Blocks
  • Carbonyl Compounds
  • Organic Building Blocks
  • Lactones