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(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN

Product Name
(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
CAS No.
500170-27-4
Chemical Name
(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
Synonyms
d[Cha4]-AVP;(DeaMino-Cys1,Cha4,Arg8)-Vasopressin;(Deamino-Cys1,β-cyclohexyl-Ala4,Arg8)-Vasopressin;(Deamino-Cys1,β-cyclohexyl-Ala?,Arg?)-Vasopressin;(DeaMino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin;(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN;3-Mercaptopropionyl-Tyr-Phe-b-cyclohexyl-Ala-Asn-Cys-Pro-Arg-Gly-NH2;(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt;3-MERCAPTOPROPIONYL-TYR-PHE-BETA-CYCLOHEXYL-ALA-ASN-CYS-PRO-ARG-GLY-NH2;(Deamino-Cys1,β-cyclohexyl-Ala?,Arg?)-Vasopressin trifluoroacetate salt
CBNumber
CB4279671
Molecular Formula
C50H71N13O11S2
Formula Weight
1094.31
MOL File
500170-27-4.mol
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(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Property

storage temp. 
Store at RT
form 
Solid
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in Water
Sequence
{Mpa}-Tyr-Phe-{Cha}-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge:Mpa1-Cys6)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FD109768
Product name
(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
Packaging
500ug
Price
$115
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109768
Product name
(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
Packaging
1mg
Price
$197
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109768
Product name
(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
Packaging
2mg
Price
$343
Updated
2021/12/16
ApexBio Technology
Product number
B5382
Product name
d[Cha4]-AVP
Packaging
1mg
Price
$484
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109768
Product name
(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
Packaging
5mg
Price
$685
Updated
2021/12/16
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(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Chemical Properties,Usage,Production

Uses

d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a Ki of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors[1][2].

References

[1] Ling Ling Cheng, et al. Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4. J Med Chem. 2004 Apr 22;47(9):2375-88. DOI:10.1021/jm030611c
[2] Cristiana Griffante, et al. Selectivity of d[Cha4]AVP and SSR149415 at human vasopressin and oxytocin receptors: evidence that SSR149415 is a mixed vasopressin V1b/oxytocin receptor antagonist. Br J Pharmacol. 2005 Nov;146(5):744-51. DOI:10.1038/sj.bjp.0706383

(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Suppliers

China 38 The Netherlands 1 United Kingdom 2 United States 3 USA 1 Global 45
Brunschwig chemie
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500170-27-4, (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSINRelated Search:

LCAT 3-MERCAPTOPROPIONYL-BETA-3-PYRIDYL-D-ALA-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 3-MERCAPTO-3-METHYL-BUTYRYL-TYR(ME)-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2, (DISULFIDE BOND) D[LEU4,LYS8]-VP 3-MERCAPTO-3-METHYL-BUTYRYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2 Desmopressin (DEAMINO-CYS1,D-ORN8)-VASOPRESSIN (DEAMINO-CYS1,VAL4,D-ARG8)-VASOPRESSIN (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN

  • (DeaMino-Cys1,Cha4,Arg8)-Vasopressin
  • 3-Mercaptopropionyl-Tyr-Phe-b-cyclohexyl-Ala-Asn-Cys-Pro-Arg-Gly-NH2
  • (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
  • d[Cha4]-AVP
  • 3-MERCAPTOPROPIONYL-TYR-PHE-BETA-CYCLOHEXYL-ALA-ASN-CYS-PRO-ARG-GLY-NH2
  • 3-MERCAPTOPROPIONYL-TYR-PHE-BETA-CYCLOHEXYL-ALA-ASN-CYS-PRO-ARG-GLY-NH2, (DISULFIDE BOND)
  • (DeaMino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin
  • (Deamino-Cys1,β-cyclohexyl-Ala?,Arg?)-Vasopressin
  • (Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
  • Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-3-cyclohexyl-L-alanyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1→5)-disulfide
  • (Deamino-Cys1,β-cyclohexyl-Ala4,Arg8)-Vasopressin
  • (Deamino-Cys1,β-cyclohexyl-Ala?,Arg?)-Vasopressin trifluoroacetate salt
  • (Deamino-Cys?,β-cyclohexyl-Ala?,Arg?)-Vasopressin trifluoroacetate salt
  • 500170-27-4
  • C50H71N13O11S2