ChemicalBook > CAS DataBase List > Cholesteryl myristate

Cholesteryl myristate

Product Name: Cholesteryl myristate
CAS No.: 1989-52-2
Chemical Name: Cholesteryl myristate
Synonyms: CM;C14:0 CE;tetradecanoate;Cholestryl myristate;CHOLESTERYL MYRISTATE;CHOLESTEROL MYRISTATE;Cholestryl myristic acid;Cholesterol Myristate >CHOLESTERYL TETRADECANOATE;Cholesterol=tetradecanoate
CBNumber: CB4280873
Molecular Formula: C41H72O2
Formula Weight: 597.01
MOL File: 1989-52-2.mol

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Cholesteryl myristate Property

Melting point:: 84 °C
Boiling point:: 589.77°C (rough estimate)
Density: 0.9309 (rough estimate)
refractive index: 1.5250 (estimate)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), Hexanes (Slightly)
form: A crystalline solid
color: White to off-white
LogP: 16.656 (est)
CAS DataBase Reference: 1989-52-2(CAS DataBase Reference)
NIST Chemistry Reference: Cholesteryl myristate(1989-52-2)
EPA Substance Registry System: Cholest-5-en-3-ol (3.beta.)-, tetradecanoate (1989-52-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S455342
Product name: CHOLESTERYL MYRISTATE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: S455342
Product name: CHOLESTERYL MYRISTATE
Purity: Aldrich
Packaging: 250mg
Price: $179
Updated: 2024/03/01

Cayman Chemical

Product number: 26439
Product name: Cholesteryl Myristate
Packaging: 500mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 26439
Product name: Cholesteryl Myristate
Packaging: 1g
Price: $61
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FC61972
Product name: Cholesterol Myristate
Packaging: 10g
Price: $62.5
Updated: 2021/12/16

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Cholesteryl myristate Chemical Properties,Usage,Production

Description

Cholesteryl myristate is a cholesterol ester. Levels of cholesteryl myristate are increased in the serum, liver, and aorta in rabbits fed a high-cholesterol diet and positively correlate with development of non-alcoholic fatty liver disease (NAFLD). Plasma levels of cholesteryl myristate also positively correlate with the presence of unstable atherosclerotic plaques in coronary artery disease. Cholesterol myristate has been used in the composition of lipid nanoparticles as drug carrier systems for drugs with low water solubility.

Uses

Cholesteryl Myristate is a natural steroid present in traditional Chinese medicine or used in tribal medicine.

Definition

ChEBI: A cholesterol ester obtained by the formal condensation of the hydroxy group of cholesterol with the carboxy group of myristic acid.

IC 50

Human Endogenous Metabolite

Purification Methods

Crystallise the myristate ester from Me2CO, EtOH/EtOAc or EtOH/Et2O or n-pentanol. Purify it also by column chromatography on silica gel and eluting with MeOH then evaporating to dryness. Recrystallise it and finally, dry it in vacuo over P2O5 and store it at -20o. [Labarière et al. Analyt Chem 30 1466 1958, Malanik & Malat Anal Chim Acta 76 464 1975, Beilstein 6 III 2638].

References

[1] EUNG JU KIM. Cholesterol-induced non-alcoholic fatty liver disease and atherosclerosis aggravated by systemic inflammation.[J]. PLoS ONE, 2014: e97841. DOI: 10.1371/journal.pone.0097841
[2] PETER J MEIKLE. Plasma lipidomic analysis of stable and unstable coronary artery disease.[J]. Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 31 11: 2723-2732. DOI: 10.1161/atvbaha.111.234096
[3] KARIN M. ROSENBLATT Heike B. Evaluation of the drug loading capacity of different lipid nanoparticle dispersions by passive drug loading[J]. European Journal of Pharmaceutics and Biopharmaceutics, 2017, 117: Pages 49-59. DOI: 10.1016/j.ejpb.2017.03.010

Cholesteryl myristate Preparation Products And Raw materials

Raw materials

Preparation Products

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1989-52-2, Cholesteryl myristateRelated Search:

STIGMASTEROL Propylamine N,N-Dimethylformamide Xylene Dimethyl ether Dimethyl sulfoxide ETHANE LANOSTEROL Dimethyl phthalate Dimethyl sulfate [(3S,8S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 2,4-dichlorobenzoate Dimethyl carbonate Dimethyl fumarate Dacthal Cholesterol LUMISTEROL Phthalates CHOLESTERYL STEARATE

MYRISTIC ACID CHOLESTEROL ESTER

Cholesterol myristate, >98%

(3β)-cholest-5-en-3-yltetradecanoate

3β-tetradecanoyloxycholest-5-ene

Cholest-5-en-3-ol (3beta)-, tetradecanoate

Cholest-5-en-3-yl myristate

Cholestryl myristate

tetradecanoate

CHOLESTERYL MYRISTATE (TETRADECANOATE)

CHOLESTERYL MYRISTATE, LIQUID CRYSTAL 99%

CHOLESTERYL TETRADECANOATE

CHOLESTERYL TETRADODEDECANOATE

CHOLESTERYL MYRISTATE

Cholest-5-en-3beta-yl myristate

CHOLESTEROL MYRISTATE

3BETA-HYDROXY-5-CHOLESTENE 3-TETRADECANOATE

[(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] tetradecanoate

5-CHOLESTEN-3-BETA-OL MYRISTATE

5-CHOLESTEN-3BETA-OL 3-TETRADECANOATE

5-Cholesten-3β-ol 3-tetradecanoate

3β-hydroxy-5-cholestene 3-tetradecanoate

Cholestryl myristic acid

Cholesteryl Tetradecanoate (Myristate)

Cholesteryl myristate, liquid crystal, 97%

3β-Hydroxy-5-cholestene 3-tetradecanoate, 5-Cholesten-3β-ol 3-tetradecanoate, Cholesteryl tetradecanoate

Cholest-5-en-3β-ol tetradecanoate

Cholesterol=tetradecanoate

Myristic acid 3β-cholesteryl ester

Tetradecanoic acid 3β-cholesteryl ester

Cholesteryl myristate,97%,liquid crystal

Cholesterol Myristate &gt

Cholest-5-en-3-ol (3β)-, 3-tetradecanoate

C14:0 CE

(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl tetradecanoate

Potassium Channel,inhibit,Endogenous Metabolite,Inhibitor,Nicotinic acetylcholine receptors,nAChR,Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,Cholesterol myristate,GABA Receptor,KcsA

5-CHOLESTEN-3β-OL MYRISTATE

5-Cholesten-3β-Ol 3-Tridecanoate

1989-52-2

C41H74O2

C41H72O2

BioChemical

Biochemicals and Reagents

Cholesterol and Derivatives

Lipids

Sterols

Steroids

Cholesteryl Compounds (Liquid Crystals)

Functional Materials

Liquid Crystals & Related Compounds